For almost 20 years, thioureas have been experiencing a renaissance of interest with the
emerged development of asymmetric organocatalysts. Due to their relatively high acidity and …

The peculiar features of gold (III) and gold (I) species include exceptional carbophilicity and,
at the same time, lone pair affinity. Such a combination offers many advantages for the …

A palladium‐catalyzed dehydrogenative coupling between diarylamines and olefins has
been discovered for the synthesis of substituted indoles. This intermolecular annulation …

Tryptophan (Trp) and tryptophan derivatives are C2-arylated. AC–H activation process
allows the preparation of both protected and unprotected arylated-Trp amino acids, directly …

The chemistry of palladium complexes has no limits. Many domino processes (even
multicomponent) are continuously appearing in the literature. Carbocyclic and heterocyclic …

A novel series of twenty 3-thiocyanato-1H-indoles, carrying diversification at positions N-1, C-
2 and C-5 of the heterocyclic core, were synthesized; their antiproliferative activity against …

This paper describes an efficient SN1‐type reaction of 3‐indolylmethanols with
miscellaneous nucleophiles, featuring a catalyst‐free procedure, low cost, wide substrate …

Background and Purpose Chemogenomics focuses on the discovery of new connections
between chemical and biological space leading to the discovery of new protein targets and …

A simple and highly efficient metal-free method has been developed for
hydroxyfluoroalkylation of indoles and imidazo [1, 2-a] pyridines via TEMPO-mediated C …

A general synthetic route to indoles from readily available anilines and epoxides by using
ruthenium catalysis is described. This straightforward transformation allows a variety of …