The role of vitamin D in osteomineral metabolism is well known. Several studies have
suggested its action on different biological mechanisms, such as nociceptive sensitivity and …

Kidney disorders have been associated with a variety of sleep-related disorders. Therefore,
researchers are placing greater emphasis on finding the role of chronic kidney disease …

Abstract Background The prevalence of Restless legs syndrome (RLS) in End Stage Renal
Disease (ESRD) patients is higher than that in the general population. However, the …

Background Patients with advanced CKD develop numerous symptoms, with a multifactorial
origin. Evidence linking mineral disorders (CKD-Mineral and Bone Disorder) and uremic …

This review presents a detailed summary of the current literature regarding RLS and vitamin
D deficiency. To our knowledge it is the first review of its kind. We review the prevalence of …

Abstract Purpose of Review Although we have seen tremendous advances in the
comprehension of CKD-MBD pathophysiology during the last few years, this was not …

Background: Uremic pruritus (UP) and restless legs syndrome (RLS) are highly prevalent
complaints among patients with end-stage renal disease (ESRD) undergoing chronic …

Background It is hypothesized that vitamin D deficiency, and calcium/phosphate imbalance
could be involved in the pathophysiology of restless leg syndrome (RLS). This systematic …

Restless leg syndrome (RLS), also called Willis Ekbom disease, can be described as an
unpleasant feeling that intensely urges the patients to move their lower limbs. RLS is …

Abstract Restless Leg Syndrome (RLS), or Willis-Ekbom disease (WED), is an irresistible
urge to move the legs, predominantly while resting, sitting, or sleeping, which disrupts sleep …