Arterial hypertension

S Brouwers, I Sudano, Y Kokubo, EM Sulaica - The Lancet, 2021 - thelancet.com
Arterial hypertension is the most important contributor to the global burden of disease;
however, disease control remains poor. Although the diagnosis of hypertension is still based …

[HTML][HTML] Association between insulin resistance and the development of cardiovascular disease

V Ormazabal, S Nair, O Elfeky, C Aguayo… - Cardiovascular …, 2018 - Springer
For many years, cardiovascular disease (CVD) has been the leading cause of death around
the world. Often associated with CVD are comorbidities such as obesity, abnormal lipid …

How western diet and lifestyle drive the pandemic of obesity and civilization diseases

W Kopp - Diabetes, metabolic syndrome and obesity: targets and …, 2019 - Taylor & Francis
Westernized populations are plagued by a plethora of chronic non-infectious degenerative
diseases, termed as “civilization diseases”, like obesity, diabetes, cardiovascular diseases …

Activation of pyroptosis and ferroptosis is involved in the hepatotoxicity induced by polystyrene microplastics in mice

Y Mu, J Sun, Z Li, W Zhang, Z Liu, C Li, C Peng, G Cui… - Chemosphere, 2022 - Elsevier
Microplastics (MPs) are new environmental pollutants and have received widespread
attention in recent years, but the toxicity of the MPs remains to be fully elucidated. To explore …

Methylglyoxal, a highly reactive dicarbonyl compound, in diabetes, its vascular complications, and other age-related diseases

CG Schalkwijk, CDA Stehouwer - Physiological reviews, 2020 - journals.physiology.org
The formation and accumulation of methylglyoxal (MGO), a highly reactive dicarbonyl
compound, has been implicated in the pathogenesis of type 2 diabetes, vascular …

[HTML][HTML] Therapeutic effects of green tea polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stress …

D Mokra, M Joskova, J Mokry - International journal of molecular sciences, 2022 - mdpi.com
(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …

[HTML][HTML] Endothelial dysfunction and platelet hyperactivity in type 2 diabetes mellitus: molecular insights and therapeutic strategies

R Kaur, M Kaur, J Singh - Cardiovascular diabetology, 2018 - Springer
The incidence and prevalence of diabetes mellitus is rapidly increasing worldwide at an
alarming rate. Type 2 diabetes mellitus (T2DM) is the most prevalent form of diabetes …

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in …

PK Whelton, RM Carey, WS Aronow, DE Casey… - Journal of the American …, 2018 - jacc.org
As early as the 1920s, and subsequently in the 1959 Build and Blood Pressure Study (S1. 5-
1) of almost 5 million adults insured between 1934 and 1954, a strong direct relationship …

[HTML][HTML] Molecular pathways associated with oxidative stress in diabetes mellitus

OM Ighodaro - Biomedicine & pharmacotherapy, 2018 - Elsevier
The role of oxidative stress in the occurrence and development of diabetes mellitus is both
critical and pivotal. Several molecular event cascade in different metabolic pathways such …

Association between metabolic syndrome and periodontitis: The role of lipids, inflammatory cytokines, altered host response, and the microbiome

FQ Pirih, S Monajemzadeh, N Singh… - Periodontology …, 2021 - Wiley Online Library
Periodontitis has been associated with many systemic diseases and conditions, including
metabolic syndrome. Metabolic syndrome is a cluster of conditions that occur concomitantly …