Multiphoton microscopy has enabled unprecedented dynamic exploration in living
organisms. A significant challenge in biological research is the dynamic imaging of features …

Molecular imaging has rapidly emerged as a discipline with the potential to impact
fundamental biomedical research and clinical practice. Within this field, optical imaging …

Abstract Characterization of how the microenvironment, or niche, regulates stem cell activity
is central to understanding stem cell biology and to developing strategies for the therapeutic …

The lung is highly vulnerable during sepsis, yet its functional deterioration accompanied by
disturbances in the pulmonary microcirculation is poorly understood. This study aimed to …

Stem cells reside in a specialized, regulatory environment termed the niche that dictates
how they generate, maintain and repair tissues,. We have previously documented that …

Corneal epithelial homeostasis and regeneration are sustained by limbal stem cells
(LSCs),,, and LSC deficiency is a major cause of blindness worldwide. Transplantation is …

The complex network structure of elastin and collagen extracellular matrix (ECM) forms the
primary load bearing components in the arterial wall. The structural and mechanobiological …

Mesenchymal stem cells (MSCs) are promising candidates for cell-based therapy to treat
several diseases and are compelling to consider as vehicles for delivery of biological …

One of the greatest challenges in cell therapy is to minimally invasively deliver a large
quantity of viable cells to a tissue of interest with high engraftment efficiency. Low and …

Rationale: High-resolution imaging of the heart in vivo is challenging owing to the difficulty in
accessing the heart and the tissue motion caused by the heartbeat. Objective: Here, we …