The role of oxidative stress in hyperuricemia and xanthine oxidoreductase (XOR) inhibitors

N Liu, H Xu, Q Sun, X Yu, W Chen… - Oxidative Medicine …, 2021 - Wiley Online Library
Uric acid is the end product of purine metabolism in humans. Hyperuricemia is a metabolic
disease caused by the increased formation or reduced excretion of serum uric acid (SUA) …

Serum uric acid and diabetes: from pathophysiology to cardiovascular disease

N Katsiki, GD Dimitriadis… - Current pharmaceutical …, 2021 - ingentaconnect.com
Hyperuricemia, has been traditionally related to nephrolithiasis and gout. However, it has
also been associated with the development of type 2 diabetes mellitus (T2DM) and …

Limosilactobacillus fermentum JL-3 isolated from “Jiangshui” ameliorates hyperuricemia by degrading uric acid

Y Wu, Z Ye, P Feng, R Li, X Chen, X Tian, R Han… - Gut …, 2021 - Taylor & Francis
Recent studies into the beneficial effects of fermented foods have shown that this class of
foods are effective in managing hyperuricemia and gout. In this study, the uric acid (UA) …

Polysaccharides from Alpinia oxyphylla fruit prevent hyperuricemia by inhibiting uric acid synthesis, modulating intestinal flora and reducing renal inflammation

F Ren, J Lin, M Zhu, R Ma, M Zhang, W Chen… - International Journal of …, 2024 - Elsevier
Hyperuricemia (HUA) is one of the most common chronic diseases today, with a prevalence
exceeding 14% in both the United States and China. Current clinical treatments for HUA …

Today's and yesterday's of pathophysiology: biochemistry of metabolic syndrome and animal models

S Aydin, A Aksoy, S Aydin, M Kalayci, M Yilmaz… - Nutrition, 2014 - Elsevier
During the past 20 y, there has been much interest in sugars and especially fructose in
relation to human health. Over the past decade, considerable scientific debate and …

Effects of extra virgin olive oil and fish oil on lipid profile and oxidative stress in patients with metabolic syndrome

D Venturini, ANC Simão, MR Urbano, I Dichi - Nutrition, 2015 - Elsevier
Objective The aim of this study was to verify if extra virgin olive oil and fish oil have a
synergistic effect on lipid and oxidative stress parameters in patients with metabolic …

The effect of metformin on urate metabolism: Findings from observational and Mendelian randomization analyses

H Dai, T Hou, Q Wang, Z Zhu, Y Zhu… - Diabetes, Obesity …, 2024 - Wiley Online Library
Aim To evaluate the effect of metformin on urate metabolism. Materials and Methods Using
the UK Biobank, we first performed association analyses of metformin use with urate levels …

Lowering the risk of hyperuricemia and gout is associated with ideal cardiovascular health

P Liu, K Kadier, C Cui, X Peng, W Hou… - Journal of Health …, 2024 - Springer
Background Hyperuricemia (HUA) and gout have been demonstrated as independent risk
factors for cardiovascular disease. The relationship between the recently updated Life's …

Simultaneous determination of uric acid, dopamine and ascorbic acid based on poly (bromocresol green) modified glassy carbon electrode

X Ouyang, L Luo, Y Ding, B Liu, D Xu… - Journal of Electroanalytical …, 2015 - Elsevier
A glassy carbon electrode modified with poly (bromocresol green) was prepared by
electropolymerization process for simultaneous determination of uric acid, dopamine and …

SIRT1 prevents hyperuricemia via the PGC-1α/PPARγ-ABCG2 pathway

J Wang, XX Zhu, L Liu, Y Xue, X Yang, HJ Zou - Endocrine, 2016 - Springer
Silent information regulator T1 (SIRT1) plays several key roles in the regulation of lipid and
glucose homoeostasis. In this study, we investigated the potential role of SIRT1 in …