Does oxidative stress shorten telomeres in vivo? A review

S Reichert, A Stier - Biology letters, 2017 - royalsocietypublishing.org
The length of telomeres, the protective caps of chromosomes, is increasingly used as a
biomarker of individual health state because it has been shown to predict chances of …

The roles of senescence and telomere shortening in cardiovascular disease

F Fyhrquist, O Saijonmaa, T Strandberg - Nature Reviews Cardiology, 2013 - nature.com
Cellular senescence, defined as arrest during the cell cycle (G0), is involved in the complex
process of the biological ageing of tissues, organs, and organisms. Senescence is driven by …

Association between the Oxidative Balance Score and Telomere Length from the National Health and Nutrition Examination Survey 1999‐2002

W Zhang, SF Peng, L Chen, HM Chen… - Oxidative medicine …, 2022 - Wiley Online Library
Purpose. Leukocyte telomere length (LTL) is an important biomarker of aging. The oxidative
balance score (OBS) is used to assess the oxidative stress‐related exposures of diet and …

Mediterranean diet and telomere length in Nurses' Health Study: population based cohort study

M Crous-Bou, TT Fung, J Prescott, B Julin, M Du, Q Sun… - Bmj, 2014 - bmj.com
Objective To examine whether adherence to the Mediterranean diet was associated with
longer telomere length, a biomarker of aging. Design Population based cohort study. Setting …

Telomere length and oxidative stress and its relation with metabolic syndrome components in the aging

G Gavia-García, J Rosado-Pérez, TL Arista-Ugalde… - Biology, 2021 - mdpi.com
Simple Summary A link between telomere length and some age-related diseases has been
identified, including metabolic syndrome. So far, there is no mechanism to explain the origin …

Telomeres and telomerase in cardiovascular diseases

JK Yeh, CY Wang - Genes, 2016 - mdpi.com
Telomeres are tandem repeat DNA sequences present at the ends of each eukaryotic
chromosome to stabilize the genome structure integrity. Telomere lengths progressively …

Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease

R Farzaneh-Far, J Lin, ES Epel, WS Harris… - Jama, 2010 - jamanetwork.com
Context Increased dietary intake of marine omega-3 fatty acids is associated with prolonged
survival in patients with coronary heart disease. However, the mechanisms underlying this …

Effect of comprehensive lifestyle changes on telomerase activity and telomere length in men with biopsy-proven low-risk prostate cancer: 5-year follow-up of a …

D Ornish, J Lin, JM Chan, E Epel, C Kemp… - The lancet …, 2013 - thelancet.com
Background Telomere shortness in human beings is a prognostic marker of ageing, disease,
and premature morbidity. We previously found an association between 3 months of …

Epigenetic regulation of genomic stability by vitamin C

JP Brabson, T Leesang, S Mohammad… - Frontiers in genetics, 2021 - frontiersin.org
DNA methylation plays an important role in the maintenance of genomic stability. Ten-
eleven translocation proteins (TETs) are a family of iron (Fe2+) and α-KG-dependent …

Telomeres and lifestyle factors: roles in cellular aging

J Lin, E Epel, E Blackburn - Mutation Research/Fundamental and Molecular …, 2012 - Elsevier
Recent research has demonstrated that telomere maintenance might be a key integrating
point for the cumulative effects of genetic, environmental and lifestyle factors on aging and …