RNA deep sequencing reveals novel candidate genes and polymorphisms in boar testis and liver tissues with divergent androstenone levels

A Gunawan, S Sahadevan, C Neuhoff… - PloS one, 2013 - journals.plos.org
Boar taint is an unpleasant smell and taste of pork meat derived from some entire male pigs.
The main causes of boar taint are the two compounds androstenone (5α-androst-16-en-3 …

Effect of polymorphisms in the GBP1, Mx1 and CD163 genes on host responses to PRRSV infection in pigs

P Niu, N Shabir, A Khatun, BJ Seo, S Gu, SM Lee… - Veterinary …, 2016 - Elsevier
Porcine reproductive and respiratory syndrome (PRRS) is the most economically important
disease to the swine industry, and effective prevention strategy for this disease is still …

Induction and antiviral activity of ferret myxovirus resistance (Mx) protein 1 against influenza A viruses

R Farrukee, LSU Schwab, JB Barnes, AG Brooks… - Scientific Reports, 2024 - nature.com
Myxovirus resistance (Mx) proteins are products of interferon stimulated genes (ISGs) and
Mx proteins of different species have been reported to mediate antiviral activity against a …

Porcine Mx1 protein inhibits classical swine fever virus replication by targeting nonstructural protein NS5B

J Zhou, J Chen, XM Zhang, ZC Gao, CC Liu… - Journal of …, 2018 - Am Soc Microbiol
Mx proteins are interferon (IFN)-induced GTPases that have broad antiviral activity against a
wide range of RNA and DNA viruses; they belong to the dynamin superfamily of large …

A Naturally Occurring Variant of Porcine Mx1 Associated with Increased Susceptibility to Influenza Virus In Vitro

E Nakajima, T Morozumi, K Tsukamoto, T Watanabe… - Biochemical …, 2007 - Springer
Mx1 has been implicated in resistance to the influenza virus. We have now identified four
alleles of the Mxl gene in domesticated breeds of pigs. Two of the alleles encode deletion …

Genomic prediction and genome-wide association study for boar taint compounds

S Faggion, E Boschi, R Veroneze, P Carnier, V Bonfatti - Animals, 2023 - mdpi.com
Simple Summary Some of the compounds involved in sexual steroids' metabolic pathways
(ie, androstenone, indole, and skatole) might accumulate in the adipose tissue of intact male …

Polymorphisms and the antiviral property of porcine Mx1 protein

A Asano, JH Ko, T Morozumi, N Hamashima… - Journal of veterinary …, 2002 - jstage.jst.go.jp
We determined the cDNA sequences of the type I interferon-inducible proteins, pig Mx1 from
PK (15) and LLC-PK1 cells, and compared the antiviral activities of both Mx proteins …

Production of transgenic pigs over-expressing the antiviral gene Mx1

Q Yan, H Yang, D Yang, B Zhao, Z Ouyang, Z Liu… - Cell Regeneration, 2014 - Springer
The myxovirus resistance gene (Mx1) has a broad spectrum of antiviral activities. It is
therefore an interesting candidate gene to improve disease resistance in farm animals. In …

Porcine Toll-like receptors: recognition of Salmonella enterica serovar Choleraesuis and influence of polymorphisms

H Shinkai, R Suzuki, M Akiba, N Okumura… - Molecular immunology, 2011 - Elsevier
Salmonella enterica serovar Choleraesuis (SC) is a highly invasive pathogen that causes
enteric and septicemic diseases in pigs. Although there have been some reports on gene …

Identification of a short interspersed repetitive element insertion polymorphism in the porcine MX1 promoter associated with resistance to porcine reproductive and …

Y Li, S Liang, H Liu, Y Sun, L Kang, Y Jiang - Animal genetics, 2015 - Wiley Online Library
The myxovirus resistance (Mx) proteins belong to the dynamin superfamily and are
important for innate host defence against RNA viruses. In this study, we demonstrate that …