Metals play vital roles in nutrients and medicines and provide chemical functionalities that
are not accessible to purely organic compounds. At least 10 metals are essential for human …

Fourier transform ion cyclotron resonance mass analysers (FT-ICR MS) can offer the highest
resolutions and mass accuracies in mass spectrometry. Mass spectra acquired in an FT-ICR …

Cisplatin and its analogues are widely used as chemotherapeutic agents in clinical practice.
After being intravenously administrated, a substantial amount of platinum will bind with …

Interactions between proteins and metal ions and their complexes are important in many
areas of the life sciences, including physiology, medicine, and toxicology. Despite the …

Two-dimensional mass spectrometry (2D MS) is a multiplexed tandem mass spectrometry
method that does not rely on ion isolation to correlate the precursor and fragment ions. On a …

The 3D structures of biomolecules determine their biological function. Established methods
in biomolecule structure determination typically require purification, crystallization, or …

Cisplatin is widely used for the treatment of various solid tumors. It is mainly administered by
intravenous injection, and a substantial amount of the drug will bind to plasma proteins, a …

Antibiotic resistance has become a primary concern in medicine because of the overuse and
misuse of classical pharmaceuticals. Recently, nonbiological complex drugs (NBCDs) have …

Modern soft ionization mass spectrometry provides chemical information on various
polymers with unparalleled resolution and sensitivity. However, the interpretation of the …

With increasing focus on the structural elucidation of polymers, advanced tandem mass
spectrometry techniques will play a crucial role in the characterization of these compounds …