Long non-coding RNAs in the regulation of gene expression: physiology and disease

JCR Fernandes, SM Acuña, JI Aoki, LM Floeter-Winter… - Non-coding RNA, 2019 - mdpi.com
The identification of RNAs that are not translated into proteins was an important
breakthrough, defining the diversity of molecules involved in eukaryotic regulation of gene …

Recent advances in diagnostic approaches for epstein–barr virus

MAH Abusalah, SH Gan, MAI Al-Hatamleh, AA Irekeola… - Pathogens, 2020 - mdpi.com
Epstein–Barr virus (EBV) is the causative agent of many diseases including infectious
mononucleosis (IM), and it is associated with different subtypes of lymphoma, sarcoma and …

Viral long non-coding RNA regulates virus life-cycle and pathogenicity

Z Li, J Gao, X Xiang, J Deng, D Gao, X Sheng - Molecular Biology Reports, 2022 - Springer
Viral infection is still a serious global health problem that kills hundreds of thousands of
people annually. Understanding the mechanism by which virus replicates, packages, and …

Role of bacterial and viral pathogens in gastric carcinogenesis

M Palrasu, E Zaika, W El-Rifai, J Que, AI Zaika - Cancers, 2021 - mdpi.com
Simple Summary Stomach cancer is one of the most common cancers in the world, with over
one million new cases diagnosed in 2020. Despite recent advances in cancer treatments …

Unveiling the druggable RNA targets and small molecule therapeutics

J Sztuba-Solinska, G Chavez-Calvillo… - Bioorganic & medicinal …, 2019 - Elsevier
The increasing appreciation for the crucial roles of RNAs in infectious and non-infectious
human diseases makes them attractive therapeutic targets. Coding and non-coding RNAs …

Viral RNA structure analysis using DMS-MaPseq

P Tomezsko, H Swaminathan, S Rouskin - Methods, 2020 - Elsevier
RNA structure is critically important to RNA viruses in every part of the replication cycle. RNA
structure is also utilized by DNA viruses in order to regulate gene expression and interact …

Long noncoding RNAs: novel regulators of virus‐host interactions

S Liu, X Liu, J Li, H Zhou, MJ Carr… - Reviews in medical …, 2019 - Wiley Online Library
Long noncoding RNAs (lncRNAs) represent a key class of cellular regulators, involved in the
modulation and control of multiple biological processes. Distinct classes of lncRNAs are now …

[HTML][HTML] Altering gene expression using antisense oligonucleotide therapy for hearing loss

KN Robillard, E de Vrieze, E van Wijk, JJ Lentz - Hearing Research, 2022 - Elsevier
Hearing loss affects more than 430 million people, worldwide, and is the third most common
chronic physical condition in the United States and Europe (GBD Hearing Loss …

Intra-host changes in Kaposi sarcoma-associated herpesvirus genomes in Ugandan adults with Kaposi sarcoma

JC Santiago, JD Goldman, H Zhao, AP Pankow… - PLoS …, 2021 - journals.plos.org
Intra-host tumor virus variants may influence the pathogenesis and treatment responses of
some virally-associated cancers. However, the intra-host variability of Kaposi sarcoma …

Viral manipulation of the host epigenome as a driver of virus-induced oncogenesis

SHAA Soliman, A Orlacchio, F Verginelli - Microorganisms, 2021 - mdpi.com
Tumorigenesis due to viral infection accounts for a high fraction of the total global cancer
burden (15–20%) of all human cancers. A comprehensive understanding of the mechanisms …