Type I interferon and the Spectrum of susceptibility to viral infection and autoimmune disease: a shared genomic signature
Type I interferons (IFN-I) and their cognate receptor, the IFNAR1/2 heterodimer, are critical
components of the innate immune system in humans. They have been widely explored in …
components of the innate immune system in humans. They have been widely explored in …
Graphene-based biosensors for molecular chronic inflammatory disease biomarker detection
Chronic inflammatory diseases, such as cancer, diabetes mellitus, stroke, ischemic heart
diseases, neurodegenerative conditions, and COVID-19 have had a high number of deaths …
diseases, neurodegenerative conditions, and COVID-19 have had a high number of deaths …
Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing
N Kessler, SF Viehmann, C Krollmann, K Mai… - Journal of Experimental …, 2022 - rupress.org
Autoimmune vasculitis is a group of life-threatening diseases, whose underlying pathogenic
mechanisms are incompletely understood, hampering development of targeted therapies …
mechanisms are incompletely understood, hampering development of targeted therapies …
Gene signature of regulatory T Cells isolated from children with selective IgA deficiency and common variable immunodeficiency
M Rutkowska-Zapała, A Grabowska-Gurgul, M Lenart… - Cells, 2024 - mdpi.com
Selective IgA deficiency (SIgAD) is the most common form and common variable
immunodeficiency (CVID) is the most symptomatic form of predominant antibody deficiency …
immunodeficiency (CVID) is the most symptomatic form of predominant antibody deficiency …
Longitudinal monitoring of circulating immune cell phenotypes in anti-neutrophil cytoplasmic antibody-associated vasculitis
K Matsumoto, K Suzuki, H Yasuoka, J Hirahashi… - Autoimmunity …, 2023 - Elsevier
Anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) is a necrotizing multiorgan
autoimmune disease that affects small-to medium-sized blood vessels. Despite the …
autoimmune disease that affects small-to medium-sized blood vessels. Despite the …
Integrated bioinformatic analysis of the shared molecular mechanisms between ANCA-associated vasculitis and atherosclerosis
X Hu, I Xu Lou, Q Chen - Arthritis Research & Therapy, 2024 - Springer
Background and objective Accumulated evidence supports the tendency of antineutrophil
cytoplasmic antibody (ANCA)-associated vasculitis (AAV) to coexist with atherosclerosis …
cytoplasmic antibody (ANCA)-associated vasculitis (AAV) to coexist with atherosclerosis …
[HTML][HTML] Targeting the Type I IFN Pathway in Glomerular Kidney Disease: Rationale and Therapeutic Opportunities
J Tumlin, B Rovin, HJ Anders, EF Mysler… - Kidney International …, 2024 - Elsevier
Type I interferons (IFNs) are immunostimulatory molecules that can activate the innate and
adaptive immune systems. In cases of immune dysfunction, prolonged activation of the type I …
adaptive immune systems. In cases of immune dysfunction, prolonged activation of the type I …
Contribution of the whole exome sequencing in the identification of genetic variants associated with childhood-onset systemic lupus and IgA vasculitis
M Šestan - 2022 - dr.nsk.hr
Introduction and aim. Childhood-onset systemic lupus erythematosus (cSLE) and IgA
vasculitis (IgAV) are two complex autoimmune diseases with etiopathogenesis which are not …
vasculitis (IgAV) are two complex autoimmune diseases with etiopathogenesis which are not …