Systematic characterization of the cancer microbiome provides a unique opportunity to
develop cancer diagnostics that exploit non-human, microbial-derived molecules in a major …

Gene expression data are accumulating exponentially in public repositories. Reanalysis and
integration of themed collections from these studies may provide new insights, but requires …

The expression microarray is a frequently used approach to study gene expression on a
genome-wide scale. However, the data produced by the thousands of microarray studies …

Background Understanding the genetic and environmental factors that structure plant
microbiomes is necessary for leveraging these interactions to address critical needs in …

Genomic data integration is a key goal to be achieved towards large-scale genomic data
analysis. This process is very challenging due to the diverse sources of information resulting …

Background The molecular signature of atopic dermatitis (AD) lesions is associated with TH
2 and TH 22 activation and epidermal alterations. However, the epidermal and dermal AD …

Aging is linked to deficiencies in immune responses and increased systemic inflammation.
To unravel the regulatory programs behind these changes, we applied systems immunology …

While multiple studies have reported the accelerated evolution of brain gene expression in
the human lineage, the mechanisms underlying such changes are unknown. Here, we …

Successful rearing of fish in hatcheries is critical for conservation, recreational fishing,
commercial fishing through wild stock enhancements, and aquaculture production …

Protein–DNA interactions are critical to the regulation of gene expression, but it remains
challenging to define how cell-to-cell heterogeneity in protein–DNA binding influences gene …