Engineered nucleic acids encoding a modified erythropoietin and their expression
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
46147671&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
46147671&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Terminally modified RNA
T Chakraborty, S Bancel, SG Hoge, A Roy… - US Patent …, 2017 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49447811&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
49447811&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Engineered nucleic acids and methods of use thereof
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C (= O) C (NC (= O)
C (CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …
C (CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …
Modified polynucleotides for the production of biologics and proteins associated with human disease
S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49235350&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
49235350&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Cationic lipids and methods for the delivery of therapeutic agents
J Heyes, L Palmer, M Maslowski… - US Patent 8,569,256, 2013 - Google Patents
0 [1*] N ([2*])([3*]) CC (COCCCCC/C= C\C/C= C\C/C= C\C [4*]) OCCCCC/C= C\C/C=
C\C/C= C\C [5*] Chemical compound [1*] N ([2*])([3*]) CC (COCCCCC/C= C\C/C= C\C/C …
C\C/C= C\C [5*] Chemical compound [1*] N ([2*])([3*]) CC (COCCCCC/C= C\C/C= C\C/C …
Lipid formulations for nucleic acid delivery
E Yaworski, K Lam, L Jeffs, L Palmer… - US Patent …, 2011 - Google Patents
The present invention provides novel, stable lipid particles comprising one or more active
agents or therapeutic agents, methods of making the lipid particles, and methods of deliv …
agents or therapeutic agents, methods of making the lipid particles, and methods of deliv …
Modified polynucleotides for the production of secreted proteins
T Chakraborty, A De Fougerolles - US Patent 9,192,651, 2015 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49235350&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
49235350&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Lipid encapsulated interfering RNA
I Maclachlan, LR Palmer, J Heyes - US Patent 7,799,565, 2010 - Google Patents
US7799565B2 - Lipid encapsulated interfering RNA - Google Patents US7799565B2 - Lipid
encapsulated interfering RNA - Google Patents Lipid encapsulated interfering RNA …
encapsulated interfering RNA - Google Patents Lipid encapsulated interfering RNA …
Cationic lipids and methods of use
J Heyes, I Maclachlan, LR Palmer - US Patent 7,745,651, 2010 - Google Patents
The present invention provides novel cationic lipids that have increased flexibility over
commonly used cationic lipids (such as DODAC and DODMA). When incorporated into lipid …
commonly used cationic lipids (such as DODAC and DODMA). When incorporated into lipid …
Engineered nucleic acids and methods of use thereof
S Bancel, JP Schrum, A Aristarkhov - US Patent 9,464,124, 2016 - Google Patents
A61K48/0075—Medicinal preparations containing genetic material which is inserted into
cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of …
cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of …