Methylenetetrahydrofolate reductase (MTHFR) is a key regulatory enzyme in the one-carbon
cycle. This enzyme is essential for the metabolism of methionine, folate, and RNA, as well as …

Abstract Background Cystic Fibrosis (CF) is an autosomal recessive disorder with life-
threatening organ manifestations. 87% of CF patients develop exocrine pancreas …

Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
spread rapidly throughout the world causing health, social and economic instability. The …

We assess the contributions of genetic variants for the enzymes involved in capecitabine
metabolism to colorectal cancer (CRC) development risk. In this case-control study, DNA …

Background This study was conducted to estimate the precise association of fetal MTHFR
677 C> T polymorphism with risk of nonsyndromic cleft lip with or without cleft palate …

Objective Genetic variation in the methylenetetrahydrofolate reductase (MTHFR) gene may
contribute to the development of cerebral infarction (CI); however, results have been …

Identification of causal factors that influence fetal growth and anthropometry at birth is of
great importance as they provide information about increased risk of disease throughout life …

The aim is to study risk factors for retinal vein occlusion (RVO), such as thrombophilic and
cardiovascular risk factors (CRF). A retrospective consecutive case series of 60 patients with …

The (MTHFR) C677T gene polymorphism is associated with neurological disorders and
schizophrenia. Patients diagnosed with schizophrenia and schizoaffective disorder and …

Background: The methylenetetrahydrofolate reductase (MTHFR) gene is an essential gene
in the metabolism of folate-homocysteine. Recently, the level of homocysteine was found to …