Immune mechanisms in the pathophysiology of hypertension

BA Nguyen, MR Alexander, DG Harrison - Nature Reviews Nephrology, 2024 - nature.com
Hypertension is a leading risk factor for morbidity and mortality worldwide. Despite current
anti-hypertensive therapies, most individuals with hypertension fail to achieve adequate …

Immunological insights into hypertension: unraveling triggers and potential therapeutic avenues

BG Shokoples, P Paradis, EL Schiffrin - Hypertension Research, 2024 - nature.com
Hypertension remains the leading cause of morbidity and mortality worldwide. Despite its
prevalence, the development of novel antihypertensive therapies has only recently …

CD28-expressing δ T cells are increased in perivascular adipose tissue of hypertensive mice and in subcutaneous adipose tissue of obese humans

O Berillo, K Comeau, A Caillon, S Leclerc… - Journal of …, 2024 - journals.lww.com
Objectives: γδ T-lymphocytes play a role in angiotensin II (AngII)-induced hypertension,
vascular injury and T-cell infiltration in perivascular adipose tissue (PVAT) in mice …