Collapse of complexity of brain and body activity due to excessive inhibition and MeCP2 disruption
J Li, PA Kells, AC Osgood… - Proceedings of the …, 2021 - National Acad Sciences
Complex body movements require complex dynamics and coordination among neurons in
motor cortex. Conversely, a long-standing theoretical notion supposes that if many neurons …
motor cortex. Conversely, a long-standing theoretical notion supposes that if many neurons …
[HTML][HTML] Substantial acetylcholine reduction in multiple brain regions of Mecp2-deficient female rats and associated behavioral abnormalities
H Murasawa, H Kobayashi, J Imai, T Nagase… - PLoS …, 2021 - journals.plos.org
Rett syndrome (RTT) is a neurodevelopmental disorder with X-linked dominant inheritance
caused mainly by mutations in the methyl-CpG-binding protein 2 (MECP2) gene. The effects …
caused mainly by mutations in the methyl-CpG-binding protein 2 (MECP2) gene. The effects …
Sensory-evoked activity in somatosensory cortex as a model to probe cortical plasticity in a mouse model of Rett syndrome
F Farhoomand - 2021 - dspace.library.uvic.ca
Rett syndrome (RTT), a severe neurodevelopmental disorder, affects females resulting from
loss-of-function mutations in the X-linked transcription factor methyl-CpG-binding protein 2 …
loss-of-function mutations in the X-linked transcription factor methyl-CpG-binding protein 2 …
Reduced complexity of brain and behavior due to MeCP2 disruption and excessive inhibition
Rett syndrome (RTT) is a devastating neurodevelopmental disorder, caused by disruptions
to the MECP2 gene, and resulting in severe cognitive and motor impairment. Previous work …
to the MECP2 gene, and resulting in severe cognitive and motor impairment. Previous work …