Therapeutic vaccines preferentially stimulate T cells against tumour-specific epitopes that
are created by DNA mutations or oncogenic viruses. In the setting of premalignant disease …

Peptide-based cancer vaccines rely upon the strong activation of the adaptive immune
response to elicit its effector function. They have shown to be highly specific and safe, but …

Toll-like receptors (TLRs) are a class of proteins that recognize pathogen-associated
molecular patterns (PAMPs) and damaged-associated molecular patterns (DAMPs), and …

At the forefront of the battle against pathogens or any endogenously released molecules, toll‐
like receptors (TLRs) play an important role as the most noble pattern recognition receptors …

The development of lipopeptides (lipidated peptides) for vaccines is discussed, including
their role as antigens and/or adjuvants. Distinct classes of lipopeptide architectures are …

Peptide vaccines have shown great potential in cancer immunotherapy by targeting tumor
antigens and activating the patient's immune system to mount a specific response against …

The murine MC-38 colorectal cancer model is a commonly used model for cancer with high
mutational burden, which is sensitive for immune checkpoint immunotherapy. We set out to …

Toll-like receptors (TLRs) are vital elements of the mammalian immune system that function
by recognizing pathogen-associated molecular patterns (PAMPs), bridging innate and …

Abstract Background Ligands for the Toll-like receptor (TLR) family can induce activation of
cells of the innate immune system and are widely studied for their potential to enhance …

Toll-like receptors (TLRs) are the pattern recognition receptors (PRRs) that recognize
pathogen-associated molecular patterns (PAMPs) in microbial species. Among the various …