GeneMAP: A discovery platform for metabolic gene function

SLC25A48 influences plasma levels of choline and localizes to the inner mitochondrial membrane

DJ Bernard, F Pangilinan, C Mendina… - Molecular Genetics and …, 2024 - Elsevier
Choline contributes to the biogenesis of methyl groups, neurotransmitters, and cell
membranes. Our genome-wide association study (GWAS) of circulating choline in 2228 …
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[HTML][HTML] Mitochondrial choline import regulates purine nucleotide pools via SLC25A48

ARP Verkerke, X Shi, I Abe, RE Gerszten, S Kajimura - bioRxiv, 2024 - ncbi.nlm.nih.gov
Choline is an essential nutrient for cellular metabolism, including the biosynthesis of
phospholipids, neurotransmitters, and one-carbon metabolism. A critical step of choline …
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