Centrosomes are microtubule-organizing centres of animal cells. They influence the
morphology of the microtubule cytoskeleton, function as the base for the primary cilium and …

The centrosome was discovered in the late 19th century when mitosis was first described.
Long recognized as a key organelle of the spindle pole, its core component, the centriole …

Formation of one procentriole next to each pre-existing centriole is essential for centrosome
duplication, robust bipolar spindle assembly and maintenance of genome integrity …

The centriole, and the related basal body, is an ancient organelle characterized by a
universal 9-fold radial symmetry and is critical for generating cilia, flagella, and centrosomes …

The centriole is an evolutionarily conserved macromolecular structure that is crucial for the
formation of flagella, cilia and centrosomes. The ultrastructure of the centriole was first …

Centriole duplication occurs once per cell cycle in order to maintain control of centrosome
number and ensure genome integrity. Polo-like kinase 4 (Plk4) is a master regulator of …

The increase in centrosome size in mitosis was described over a century ago, and yet it is
poorly understood how centrioles, which lie at the core of centrosomes, organize the …

Centriole duplication involves the growth of a procentriole next to the parental centriole.
Mutations in STIL and CPAP/CENPJ cause primary microcephaly (MCPH). Here, we show …

Centrosomes are the main microtubule-organizing centre of animal cells and are important
for many critical cellular and developmental processes from cell polarization to cell division …

Centrioles are microtubule-based core components of centrosomes and cilia. They are
duplicated exactly once during S-phase progression. Central to formation of each new …