Highlights•One-carbon compounds can be made from CO 2 to provide renewable microbial
feedstocks.•Methanol and formate have key advantages over gaseous one-carbon …

BACKGROUND Environmental, geopolitical, and economic factors are reshaping our view
of global energy and manufacturing demands. Addressing these challenges may require a …

The dependence on fossil fuels has caused excessive emissions of greenhouse gases
(GHGs), leading to climate changes and global warming. Even though the expansion of …

Global climate change caused by the accumulation of greenhouse gases (GHGs) has
caused concerns regarding the continued reliance on fossil fuels as our primary energy …

Sustainable production of chemicals and materials from renewable non-food biomass using
biorefineries has become increasingly important in an effort toward the vision of 'net zero …

We show that CO2 can be converted by an engineered “Knallgas” bacterium (Cupriavidus
necator) into the terpene α‐humulene. Heterologous expression of the mevalonate pathway …

Terpenoid flavor and fragrance compounds are of high interest to the aroma industry.
Microbial production offers an alternative sustainable access to the desired terpenoids …

Limonene and its derivatives have great market potential with diverse applications in food,
pharmaceuticals, cosmetics, etc. Commercial production of limonene and its derivatives …

Methanol represents an attractive substrate for biotechnological applications. Utilization of
reduced one-carbon compounds for growth is currently limited to methylotrophic organisms …

More than 70,000 different terpenoid structures are known so far; many of them offer highly
interesting applications as pharmaceuticals, flavors and fragrances, or biofuels. Extraction of …