Simple Summary Cancer is increasingly viewed as a cell cycle disease in that the
dysregulation of the cell cycle machinery is a common feature in cancer. The Hippo …

Over the past decade, the Hippo tumor suppressor pathway has emerged as a central
regulator of growth in epithelial tissues. Research in Drosophila and in mammals has shown …

Abnormalities in dendritic spines are manifestations of several neurodevelopmental and
psychiatric diseases. TAOK2 is one of the genes in the 16p11. 2 locus, copy number …

Thousand and one amino‐acid kinase 1 (TAOK1) is a MAP3K protein kinase, regulating
different mitogen‐activated protein kinase pathways, thereby modulating a multitude of …

Drosophila melanogaster has become a significant model organism for alcohol research. In
flies, a rich variety of behaviors can be leveraged for identifying genes affecting alcohol …

Dendritic arborization is highly regulated and requires tight control of dendritic growth,
branching, cytoskeletal dynamics, and ion channel expression to ensure proper function …

Neuronal signal transduction by the JNK MAP kinase pathway is altered by a broad array of
stimuli including exposure to the widely abused drug ethanol, but the behavioral relevance …

Despite the complexity of neurodevelopmental disorders (NDDs), from their genotype to
phenotype, in the last few decades substantial progress has been made in understanding …

Chromosomal instability can arise from defects in chromosome–microtubule attachment.
Using a variety of drug treatments, we show that TAO1 kinase is required for ensuring the …

Sensory circuits are typically established during early development, yet how circuit
specificity and function are maintained during organismal growth has not been elucidated …