Individuals with spinal cord injury (SCI) often experience bone loss and muscle atrophy.
Muscle atrophy can result in reduced metabolic rate and increase the risk of metabolic …

Osteoporosis is a known consequence of spinal cord injury (SCI) and occurs in almost every
SCI patient. It manifests itself as an increase in the incidence of lower extremity fractures …

Osteoporosis is a multifactorial disorder of bone mineral homeostasis affecting the elderly. It
is a major public health issue with significant socioeconomic consequences. Recent findings …

The paralyzed musculoskeletal system retains a remarkable degree of plasticity after spinal
cord injury (SCI). In response to reduced activity, muscle atrophies and shifts toward a fast …

Osteoporosis is a known complication of spinal cord injury (SCI), but its mechanism remains
unknown. The pathogenesis of osteoporosis after SCI is generally considered disuse …

Spinal cord injury causes rapid, severe osteoporosis with increased fracture risk.
Mechanical unloading after paralysis results in increased osteocyte expression of sclerostin …

In the assessment of osteoporosis, the measurement of bone mineral density (BMDa)
obtained from dual energy X-ray absorptiometry (DXA; g/cm2) is the most widely used …

Maintaining the physiologic integrity of paralyzed limbs may be critical for those with spinal
cord injury (SCI) to be viable candidates for a future cure. No long-term intervention has …

Study design: Systematic review. Objective: To systematically review evidence on aging of
the body systems after spinal cord injury (SCI). Setting: Toronto, Ontario and Vancouver …

Soft tissue material properties are vital to human body models that evaluate interactions
between the human body and its environment. Such models evaluate internal stress/strain …