Obesity is a global epidemic characterized by energy disequilibrium, metabolic disorder, fat
mass development, and chronic low-grade inflammation, which significantly affects the …

Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

Development is a complex process regulated both by genetic and epigenetic and
environmental clues. Recently, long non-coding RNAs (lncRNAs) have emerged as key …

Atherosclerosis is a chronic inflammatory disease that involves the accumulation of lipids
and immune cells in the arterial wall. NF-kB signaling is a key regulator of inflammation and …

Obesity is an alarming disease that favors the upset of other illnesses and enhances
mortality. It is spreading fast worldwide may affect more than 1 billion people by 2030. The …

Background Osteoarthritis (OA), a multifaceted condition, poses a significant challenge for
the successful clinical development of therapeutics due to heterogeneity. However …

Obesity is an evolutionary, chronic, and relapsing disease that consists of a pathological
accumulation of adipose tissue able to increase morbidity for high blood pressure, type 2 …

Obesity and chronic low-grade inflammation, often occurring together, significantly
contribute to severe metabolic and inflammatory conditions like type 2 diabetes (T2D) …

Sarcopenia, broadly defined as the age-related decline in skeletal muscle mass, quality, and
function, is associated with chronic low-grade inflammation and an increased likelihood of …

It is known that long intergenic non-protein coding RNA 00707 (LINC00707) promotes
lipopolysaccharide (LPS)-injury and microRNA-199-3p (miR-199-3p) regulates chondrocyte …