Breast cancer is the most commonly diagnosed cancer in the USA. Although advances in
treatment over the past several decades have significantly improved the outlook for this …

Invasive lobular carcinoma (ILC) accounts for 10% to 15% of breast cancers in the United
States, 80% of which are estrogen receptor (ER)-positive, with an unusual metastatic pattern …

Metastatic breast cancer cells disseminate to organs with a soft microenvironment. Whether
and how the mechanical properties of the local tissue influence their response to treatment …

The pattern of delayed recurrence in a subset of breast cancer patients has long been
explained by a model that incorporates a variable period of cellular or tumor mass dormancy …

Solid cancers frequently relapse with distant metastasis, despite local and systemic
treatment. Cellular dormancy has been identified as an important mechanism underlying …

Breast cancer (BC) remains the most common cancer, as well as the leading cause of
cancer mortality in women worldwide. Approximately 30% of patients with early-stage BC …

Incomplete understanding of metastatic disease mechanisms continues to hinder effective
treatment of cancer. Despite remarkable advancements toward the identification of …

While numerous therapies are highly efficacious in early-stage breast cancers and in
particular subsets of breast cancers, therapeutic resistance and metastasis unfortunately …

Major progress in the understanding and treatment of cancer have tremendously improved
our knowledge of this complex disease and improved the length and quality of patients' …

Simple Summary Accurate in vitro modeling of diseases is essential to making breakthrough
and clinically relevant discoveries. Assays to examine the process of invasion—a classical …