Dietary lipids, gut microbiota and lipid metabolism

M Schoeler, R Caesar - Reviews in endocrine and metabolic disorders, 2019 - Springer
The gut microbiota is a central regulator of host metabolism. The composition and function of
the gut microbiota is dynamic and affected by diet properties such as the amount and …

Anti-inflammatory action of statins in cardiovascular disease: the role of inflammasome and toll-like receptor pathways

K Koushki, SK Shahbaz, K Mashayekhi… - Clinical reviews in …, 2021 - Springer
Atherosclerosis is one type of cardiovascular disease (CVD) in which activation of the
NLRP3 inflammasome and toll-like receptor (TLR) pathways is implicated. One of the most …

Nicotinamide for the treatment of heart failure with preserved ejection fraction

M Abdellatif, V Trummer-Herbst, F Koser… - Science translational …, 2021 - science.org
Heart failure with preserved ejection fraction (HFpEF) is a highly prevalent and intractable
form of cardiac decompensation commonly associated with diastolic dysfunction. Here, we …

Akkermansia Muciniphila Protects Against Atherosclerosis by Preventing Metabolic Endotoxemia-Induced Inflammation in Apoe−/− Mice

J Li, S Lin, PM Vanhoutte, CW Woo, A Xu - Circulation, 2016 - Am Heart Assoc
Background—Altered composition of the gut microbiota is involved in both the onset and
progression of obesity and diabetes mellitus. However, the link between gut microbiota and …

Toll‐like receptor polymorphism in host immune response to infectious diseases: A review

S Mukherjee, S Huda… - Scandinavian journal of …, 2019 - Wiley Online Library
Immunopolymorphism is considered as an important aspect behind the resistance or
susceptibility of the host to an infectious disease. Over the years, researchers have explored …

Innate sensing of oxidation-specific epitopes in health and disease

CJ Binder, N Papac-Milicevic, JL Witztum - Nature Reviews …, 2016 - nature.com
Ageing, infections and inflammation result in oxidative stress that can irreversibly damage
cellular structures. The oxidative damage of lipids in membranes or lipoproteins is one of …

Lipidomics profiling and risk of cardiovascular disease in the prospective population-based Bruneck study

C Stegemann, R Pechlaner, P Willeit, SR Langley… - Circulation, 2014 - Am Heart Assoc
Background—The bulk of cardiovascular disease risk is not explained by traditional risk
factors. Recent advances in mass spectrometry allow the identification and quantification of …

Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease

G Targher, CP Day, E Bonora - New England Journal of Medicine, 2010 - Mass Medical Soc
Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease | New England
Journal of Medicine Skip to main content The New England Journal of Medicine homepage …

Fast food fever: reviewing the impacts of the Western diet on immunity

IA Myles - Nutrition journal, 2014 - Springer
While numerous changes in human lifestyle constitute modern life, our diet has been
gaining attention as a potential contributor to the increase in immune-mediated diseases …

IBD—what role do Proteobacteria play?

I Mukhopadhya, R Hansen, EM El-Omar… - Nature reviews …, 2012 - nature.com
The gastrointestinal microbiota has come to the fore in the search for the causes of IBD. This
shift has largely been driven by the finding of genetic polymorphisms involved in …