Terpenoids from the medicinal mushroom Antrodia camphorata: Chemistry and medicinal potential

Y Kuang, B Li, Z Wang, X Qiao, M Ye - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to February 2020 Antrodia camphorata is a medicinal mushroom endemic to
Taiwan for the treatment of intoxication, liver injury, cancer, and inflammation. Owing to its …

Modulation of neuroinflammatory pathways by medicinal mushrooms, with particular relevance to Alzheimer's disease

N Kushairi, NAKA Tarmizi, CW Phan… - Trends in Food Science …, 2020 - Elsevier
Background Alzheimer's disease (AD) is a significant cause of dementia demonstrated by
severe and progressive cognitive impairment. While the deposition of amyloid beta (Aβ) …

Hepatoprotective activities of Antrodia camphorata and its triterpenoid compounds against CCl4-induced liver injury in mice

Z Li, Y Kuang, S Tang, K Li, Y Huang, X Qiao… - Journal of …, 2017 - Elsevier
Ethnopharmacology relevance Antrodia camphorata (AC) is a rare and precious fungus
indigenous to Taiwan used as a traditional medicine for the treatment of liver injury …

Triterpenes and Meroterpenes with Neuroprotective Effects from Ganoderma leucocontextum

H Chen, J Zhang, J Ren, W Wang… - Chemistry & …, 2018 - Wiley Online Library
Ganoderma leucocontextum is a well‐known medicinal mushroom cultivated in the Tibet
Plateau of China. Chemistry investigation on the fruiting bodies of this mushroom resulted in …

Antrodia cinnamomea and its compound dehydroeburicoic acid attenuate nonalcoholic fatty liver disease by upregulating ALDH2 activity

Y Cao, S Yue, A Wang, L Xu, Y Hu, X Qiao… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Nonalcoholic fatty liver disease (NAFLD) is a prevalent
liver disease, but currently has no specific medication in clinic. Antrodia cinnamomea (AC) is …

Separation of 25R/S-ergostane triterpenoids in the medicinal mushroom Antrodia camphorata using analytical supercritical-fluid chromatography

X Qiao, R An, Y Huang, S Ji, L Li, Y Tzeng… - … of Chromatography A, 2014 - Elsevier
Ergostanes are major bioactive constituents of the medicinal mushroom Antrodia
camphorata. These tetracyclic triterpenoids usually occur as 25R/S epimeric pairs, which …

Current advances on the structure, bioactivity, synthesis, and metabolic regulation of novel ubiquinone derivatives in the edible and medicinal mushroom Antrodia …

BB Zhang, PF Hu, J Huang, YD Hu… - Journal of agricultural …, 2017 - ACS Publications
In recent years, Antrodia cinnamomea has attracted great attention around the world as an
extremely precious edible and medicinal mushroom. Ubiquinone derivatives, which are …

A network pharmacology-based strategy to explore the pharmacological mechanisms of Antrodia camphorata and antcin K for treating type II diabetes mellitus

Y Kuang, Y Chai, H Su, JY Lo, X Qiao, M Ye - Phytomedicine, 2022 - Elsevier
Background Diabetes mellitus is a chronic carbohydrate metabolism disorder, which could
develop a series of complications and thus lead to poor quality of life or even mortality …

Metabolites identification and multi-component pharmacokinetics of ergostane and lanostane triterpenoids in the anticancer mushroom Antrodia cinnamomea

X Qiao, Q Wang, S Ji, Y Huang, Z Zhang, T Bo… - … of Pharmaceutical and …, 2015 - Elsevier
Antrodia cinnamomea is a precious medicinal mushroom popularly used for adjuvant cancer
therapy in Taiwan. Its major bioactive constituents are ergostane and lanostane …

Identification of Key Post‐modification Enzymes Involved in the Biosynthesis of Lanostane‐type Triterpenoids in the Medicinal Mushroom Antrodia camphorata

YQ Zhang, M Zhang, Z Wang, YO Bao… - Angewandte Chemie …, 2024 - Wiley Online Library
Lanostane‐type triterpenoids are important bioactive secondary metabolites of mushrooms,
though their biosynthetic study has been challenging due to scattered genes. Herein, the …