BACKGROUND Modern reproductive behavior in most developed countries is characterized
by delayed parenthood. Older gametes are generally less fertile, accumulating and …

The average age of fathers at first pregnancy has risen significantly over the last decade
owing to various variables, including a longer life expectancy, more access to contraception …

INTRODUCTION Telomeres are DNA-protein complexes located at the end of chromosomes
that protect chromosome ends from degradation and fusion. The DNA component of …

Over the last decade, there has been a significant increase in average paternal age when
the first child is conceived, either due to increased life expectancy, widespread use of …

One of the major causes of defective sperm function is oxidative stress, which not only
disrupts the integrity of sperm DNA but also limits the fertilizing potential of these cells as a …

The study aims to discuss the effects of aging on the male reproductive system. A systematic
review was performed using PubMed from 1980 to 2014. Aging is a natural process …

Epidemiological studies have principally relied on measurements of telomere length (TL) in
leucocytes, which reflects TL in other somatic cells. Leucocyte TL (LTL) displays vast …

The average length of telomere repeats (TL) declines with age and is considered to be a
marker of biological ageing. Here, we measured TL in six blood cell types from 1046 …

The idea that there is an impenetrable barrier that separates the germline and soma has
shaped much thinking in evolutionary biology and in many other disciplines. However …

Telomeres are specialised structures at the end of linear chromosomes. They consist of
tandem repeats of the hexanucleotide sequence TTAGGG, as well as a protein complex …