AEON. py: Python library for attractor analysis in asynchronous Boolean networks

N Beneš, L Brim, O Huvar, S Pastva, D Šafránek… - …, 2022 - academic.oup.com
AEON. py is a Python library for the analysis of the long-term behaviour in very large
asynchronous Boolean networks. It provides significant computational improvements over …

AEON: attractor bifurcation analysis of parametrised Boolean networks

N Beneš, L Brim, J Kadlecaj, S Pastva… - … Aided Verification: 32nd …, 2020 - Springer
Boolean networks (BNs) provide an effective modelling tool for various phenomena from
science and engineering. Any long-term behaviour of a BN eventually converges to a so …

Temporary and permanent control of partially specified Boolean networks

L Brim, S Pastva, D Šafránek, E Šmijáková - Biosystems, 2023 - Elsevier
Boolean networks (BNs) are a well-accepted modelling formalism in computational systems
biology. Nevertheless, modellers often cannot identify only a single BN that matches the …

Repository of logically consistent real-world Boolean network models

S Pastva, D Šafránek, N Beneš, L Brim, T Henzinger - bioRxiv, 2023 - biorxiv.org
Recent developments in both computational analysis and data-driven synthesis enable a
new era of automated reasoning with logical models (Boolean networks in particular) in …

Parallel one-step control of parametrised Boolean networks

L Brim, S Pastva, D Šafránek, E Šmijáková - Mathematics, 2021 - mdpi.com
Boolean network (BN) is a simple model widely used to study complex dynamic behaviour of
biological systems. Nonetheless, it might be difficult to gather enough data to precisely …

BDD-based algorithm for SCC decomposition of edge-coloured graphs

N Beneš, L Brim, S Pastva… - Logical Methods in …, 2022 - lmcs.episciences.org
Edge-coloured directed graphs provide an essential structure for modelling and analysis of
complex systems arising in many scientific disciplines (eg feature-oriented systems, gene …

Robust control of partially specified boolean networks

L Brim, S Pastva, D Šafránek, E Šmijáková - arXiv preprint arXiv …, 2022 - arxiv.org
Regulatory networks (RNs) are a well-accepted modelling formalism in computational
systems biology. The control of RNs is currently receiving a lot of attention because it …

Symbolic coloured SCC decomposition

N Beneš, L Brim, S Pastva, D Šafránek - … , TACAS 2021, Held as Part of the …, 2021 - Springer
Problems arising in many scientific disciplines are often modelled using edge-coloured
directed graphs. These can be enormous in the number of both vertices and colours. Given …

BNClassifier: Classifying Boolean Models by Dynamic Properties

N Beneš, L Brim, O Huvar, S Pastva… - … Computational Methods in …, 2024 - Springer
Abstract Partially Specified Boolean Networks (PSBNs) represent a family of Boolean
models resulting from possible interpretations of unknown update logics. Hybrid extension of …

AEON 2021: bifurcation decision trees in Boolean networks

N Beneš, L Brim, S Pastva, D Šafránek - Computational Methods in …, 2021 - Springer
Aeon is a recent tool which enables efficient analysis of long-term behaviour of
asynchronous Boolean networks with unknown parameters. In this tool paper, we present a …