Searching for the autoimmune thyroid disease susceptibility genes: from gene mapping to gene function

Y Tomer, TF Davies - Endocrine reviews, 2003 - academic.oup.com
The autoimmune thyroid diseases (AITD) are complex diseases that are caused by an
interaction between susceptibility genes and environmental triggers. Genetic susceptibility …

Immunogenetics of type 1 diabetes mellitus

MP Morran, A Vonberg, A Khadra… - Molecular aspects of …, 2015 - Elsevier
Type 1 diabetes mellitus (T1DM) is an autoimmune disease arising through a complex
interaction of both genetic and immunologic factors. Similar to the majority of autoimmune …

[图书][B] Thompson & Thompson Genetics in Medicine E-Book: Thompson & Thompson Genetics in Medicine E-Book

RL Nussbaum, RR McInnes, HF Willard - 2015 - books.google.com
Updated to reflect the newest changes in genetics, Thompson & Thompson's Genetics in
Medicine returns as one of the most favored texts in this fascinating and rapidly evolving …

The etiology of autoimmune thyroid disease: a story of genes and environment

Y Tomer, A Huber - Journal of autoimmunity, 2009 - Elsevier
Autoimmune thyroid diseases (AITDs), including Graves' disease (GD) and Hashimoto's
thyroiditis (HT) are prevalent autoimmune diseases, affecting up to 5% of the general …

Allele-specific enzymatic amplification of beta-globin genomic DNA for diagnosis of sickle cell anemia.

DY Wu, L Ugozzoli, BK Pal… - Proceedings of the …, 1989 - National Acad Sciences
A rapid nonradioactive approach to the diagnosis of sickle cell anemia is described based
on an allele-specific polymerase chain reaction (ASPCR). This method allows direct …

Non‐hierarchical logistic models and case‐only designs for assessing susceptibility in population‐based case‐control studies

WW Piegorsch, CR Weinberg, JA Taylor - Statistics in medicine, 1994 - Wiley Online Library
This article describes how genetic components of disease susceptibility can be evaluated in
case‐control studies, where cases and controls are sampled independently from the …

[图书][B] Fundamentals of genetic epidemiology

MJ Khoury, TH Beaty, BH Cohen - 1993 - books.google.com
With continued progress in mapping and sequencing of the human genome, and increasing
recognition of the role of genes in disease etiology, there is a need for a more sophisticated …

Autoimmune diseases: the failure of self tolerance

AA Sinha, MT Lopez, HO McDevitt - Science, 1990 - science.org
The ability to discriminate between self and nonself antigens is vital to the functioning of the
immune system as a specific defense against invading microorganisms. Failure of the …

Genetic susceptibility to autoimmune thyroid disease: past, present, and future

Y Tomer - Thyroid, 2010 - liebertpub.com
Background: Autoimmune thyroid diseases (AITD), including Graves' disease and
Hashimoto's thyroiditis, arise due to complex interactions between environmental and …

Joint genetic susceptibility to type 1 diabetes and autoimmune thyroiditis: from epidemiology to mechanisms

A Huber, F Menconi, S Corathers… - Endocrine …, 2008 - academic.oup.com
Abstract Type 1 diabetes (T1D) and autoimmune thyroid diseases (AITD) frequently occur
together within families and in the same individual. The co-occurrence of T1D and AITD in …