MP Morran, A Vonberg, A Khadra… - Molecular aspects of …, 2015 - Elsevier
Type 1 diabetes mellitus (T1DM) is an autoimmune disease arising through a complex interaction of both genetic and immunologic factors. Similar to the majority of autoimmune …
Updated to reflect the newest changes in genetics, Thompson & Thompson's Genetics in Medicine returns as one of the most favored texts in this fascinating and rapidly evolving …
Y Tomer, A Huber - Journal of autoimmunity, 2009 - Elsevier
Autoimmune thyroid diseases (AITDs), including Graves' disease (GD) and Hashimoto's thyroiditis (HT) are prevalent autoimmune diseases, affecting up to 5% of the general …
DY Wu, L Ugozzoli, BK Pal… - Proceedings of the …, 1989 - National Acad Sciences
A rapid nonradioactive approach to the diagnosis of sickle cell anemia is described based on an allele-specific polymerase chain reaction (ASPCR). This method allows direct …
This article describes how genetic components of disease susceptibility can be evaluated in case‐control studies, where cases and controls are sampled independently from the …
With continued progress in mapping and sequencing of the human genome, and increasing recognition of the role of genes in disease etiology, there is a need for a more sophisticated …
AA Sinha, MT Lopez, HO McDevitt - Science, 1990 - science.org
The ability to discriminate between self and nonself antigens is vital to the functioning of the immune system as a specific defense against invading microorganisms. Failure of the …
Background: Autoimmune thyroid diseases (AITD), including Graves' disease and Hashimoto's thyroiditis, arise due to complex interactions between environmental and …
A Huber, F Menconi, S Corathers… - Endocrine …, 2008 - academic.oup.com
Abstract Type 1 diabetes (T1D) and autoimmune thyroid diseases (AITD) frequently occur together within families and in the same individual. The co-occurrence of T1D and AITD in …