The ins-and-outs of exosome biogenesis, secretion, and internalization

SB Arya, SP Collie, CA Parent - Trends in cell biology, 2024 - cell.com
Exosomes are specialized cargo delivery vesicles secreted from cells by fusion of
multivesicular bodies (MVBs) with the plasma membrane (PM). While the function of …

[HTML][HTML] Modern isolation and separation techniques for extracellular vesicles

T Liangsupree, E Multia, ML Riekkola - Journal of Chromatography A, 2021 - Elsevier
Extracellular vesicles (EVs) are heterogenous membrane-bound vesicles released from
various origins. EVs play a crucial role in cellular communication and mediate several …

Liposomes and extracellular vesicles as drug delivery systems: A comparison of composition, pharmacokinetics, and functionalization

L van der Koog, TB Gandek… - Advanced healthcare …, 2022 - Wiley Online Library
Over the past decades, lipid‐based nanoparticle drug delivery systems (DDS) have caught
the attention of researchers worldwide, encouraging the field to rapidly develop improved …

Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles

G Bordanaba-Florit, F Royo, SG Kruglik… - Nature …, 2021 - nature.com
Extracellular vesicles (EVs) are heterogeneous lipid containers with a complex molecular
cargo comprising several populations with unique roles in biological processes. These …

Native and bioengineered extracellular vesicles for cardiovascular therapeutics

RC de Abreu, H Fernandes… - Nature reviews …, 2020 - nature.com
Extracellular vesicles (EVs) are a heterogeneous group of natural particles that are relevant
to the treatment of cardiovascular diseases. These endogenous vesicles have certain …

Extracellular vesicle isolation methods: rising impact of size-exclusion chromatography

M Monguió-Tortajada, C Gálvez-Montón… - Cellular and Molecular …, 2019 - Springer
Extracellular vesicles (EVs) include a variety of nanosized vesicles released to the
extracellular microenvironment by the vast majority of cells transferring bioactive lipids …

[HTML][HTML] Chemically functionalised graphene FET biosensor for the label-free sensing of exosomes

D Kwong Hong Tsang, TJ Lieberthal, C Watts… - Scientific reports, 2019 - nature.com
A graphene field-effect transistor (gFET) was non-covalently functionalised with 1-
pyrenebutyric acid N-hydroxysuccinimide ester and conjugated with anti-CD63 antibodies …

Exosome origin determines cell targeting and the transfer of therapeutic nanoparticles towards target cells

M Sancho-Albero, N Navascués, G Mendoza… - Journal of …, 2019 - Springer
Background Exosomes are considered key elements for communication between cells, but
very little is known about the mechanisms and selectivity of the transference processes …

Extracellular vesicles: techniques and biomedical applications related to single vesicle analysis

J Zhang, J Wu, G Wang, L He, Z Zheng, M Wu… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) are extensively dispersed lipid bilayer membrane vesicles
involved in the delivery and transportation of molecular payloads to certain cell types to …

Scalable production of human mesenchymal stromal cell-derived extracellular vesicles under serum-/xeno-free conditions in a microcarrier-based bioreactor culture …

M de Almeida Fuzeta, N Bernardes… - Frontiers in Cell and …, 2020 - frontiersin.org
Mesenchymal stromal cells (MSC) hold great promise for tissue engineering and cell-based
therapies due to their multilineage differentiation potential and intrinsic immunomodulatory …