Systemic pharmacological treatments for chronic plaque psoriasis: a network meta‐analysis

E Sbidian, A Chaimani, R Guelimi… - Cochrane Database …, 2023 - cochranelibrary.com
Background Psoriasis is an immune‐mediated disease with either skin or joints
manifestations, or both, and it has a major impact on quality of life. Although there is …

Exploration and development of PPAR modulators in health and disease: an update of clinical evidence

HS Cheng, WR Tan, ZS Low, C Marvalim… - International journal of …, 2019 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that govern the
expression of genes responsible for energy metabolism, cellular development, and …

Psoriasis and cardiovascular risk: a comprehensive review

W Masson, M Lobo, G Molinero - Advances in therapy, 2020 - Springer
Psoriasis is a systemic inflammatory disorder that involves complex pathogenic interactions
between the innate and adaptive immune systems. Individuals with psoriasis have an …

S3–Guidelines on the treatment of psoriasis vulgaris (English version). Update

A Nast, WH Boehncke, U Mrowietz… - JDDG: Journal der …, 2012 - Wiley Online Library
Psoriasis vulgaris is a common and often chronic inflammatory skin disease. The incidence
of psoriasis in Western industrialized countries ranges from 1.5% to 2%. Patients afflicted …

Healing fats of the skin: the structural and immunologic roles of the ω-6 and ω-3 fatty acids

MM McCusker, JM Grant-Kels - Clinics in dermatology, 2010 - Elsevier
Linoleic acid (18: 2ω6) and α-linolenic acid (18: 3ω3) represent the parent fats of the two
main classes of polyunsaturated fatty acids: the ω-6 (n-6) and the ω-3 (n-3) fatty acids …

The role of transcription factor PPAR-γ in the pathogenesis of psoriasis, skin cells, and immune cells

VV Sobolev, E Tchepourina, IM Korsunskaya… - International Journal of …, 2022 - mdpi.com
The peroxisome proliferator-activated receptor PPAR-γ is one of three PPAR nuclear
receptors that act as ligand-activated transcription factors. In immune cells, the skin, and …

Advances in the treatment of type 2 diabetes mellitus

ZH Israili - American journal of therapeutics, 2011 - journals.lww.com
There is a rising worldwide prevalence of diabetes, especially type 2 diabetes mellitus (T 2
DM), which is one of the most challenging health problems in the 21st century. The …

German S3-guidelines on the treatment of psoriasis vulgaris (short version)

A Nast, WH Boehncke, U Mrowietz… - Archives of …, 2012 - Springer
Psoriasis vulgaris is a common and often chronic inflammatory skin disease. The incidence
of psoriasis in Western industrialized countries ranges from 1.5 to 2%. Patients afflicted with …

Systematic review and recommendations to combine newer therapies with conventional therapy in psoriatic disease

S Arora, P Das, G Arora - Frontiers in Medicine, 2021 - frontiersin.org
Background: Psoriasis continues to have unmet needs in its management despite
introduction of newer molecules. Monotherapy with these newer agents may not achieve …

The role of PPARγ‐mediated signalling in skin biology and pathology: new targets and opportunities for clinical dermatology

Y Ramot, A Mastrofrancesco, E Camera… - Experimental …, 2015 - Wiley Online Library
Peroxisome proliferator‐activated receptors (PPAR s) are ligand‐activated transcription
factors that modulate the expression of multiple different genes involved in the regulation of …