The intracellular environment represents an extremely crowded milieu, with a limited amount
of free water and an almost complete lack of unoccupied space. Obviously, slightly salted …

A ubiquitous observation in cell biology is that the diffusive motion of macromolecules and
organelles is anomalous, and a description simply based on the conventional diffusion …

Approximately half of human genes generate mRNAs with alternative 3′ untranslated
regions (3′ UTRs). Through 3′ UTR-mediated protein-protein interactions, alternative 3 …

In the pursuit of dendrimer alternatives, hyperbranched polymers have found increasing
interest from academia and industry in a broad range of fields due to their topological and …

The effects of crowding in biological environments on biomolecular structure, dynamics, and
function remain not well understood. Computer simulations of atomistic models of …

Proteins are essential and abundant components of cellular membranes. Being densely
packed within the limited surface area, proteins fulfil essential tasks for life, which include …

A comprehensive understanding of protein folding and biomolecular self-assembly in the
intracellular environment requires obtaining a microscopic view of the crowding effects. The …

Excluded-volume effects can play an important role in determining transport properties in
diffusion of particles. Here, the diffusion of finite-sized hard-core interacting particles in two …

The dynamics of colloids and proteins in dense suspensions is of fundamental importance,
from a standpoint of understanding the biophysics of proteins in the cytoplasm and for the …

Macromolecular crowding is used by tissue engineers to accelerate extracellular matrix
assembly in vitro, however, most mechanistic studies focus on the impact of crowding on …