Our understanding of the structure and function of mitotic chromosomes has come a long
way since these iconic objects were first recognized more than 140 years ago, though many …

Kinesins, the microtubule-dependent mechanochemical enzymes, power a variety of
intracellular movements. Regulation of Kinesin activity and Kinesin-Cargo interactions …

During mitosis, the condensin I and II complexes compact chromatin into chromosomes.
Loss of the chromokinesin, KIF4A, results in reduced condensin I association with …

The recruitment of substrates by the ser/thr protein phosphatase 2A (PP2A) is poorly
understood, limiting our understanding of PP2A-regulated signaling. Recently, the first …

Most legumes can form an endosymbiotic association with soil bacteria called rhizobia,
which colonize specialized root structures called nodules where they fix nitrogen. To …

During cell division, the microtubule cytoskeleton undergoes dramatic cell cycle-driven
reorganizations of its architecture. Coordinated by changes in the phosphorylation patterns …

Genomes are organised into DNA loops by the Structural Maintenance of Chromosomes
(SMC) proteins. SMCs establish functional chromosomal sub-domains for DNA repair, gene …

Accurate chromosome segregation requires a complete restructuring of cellular
organization. Microtubules remodel to assemble a mitotic spindle and the actin cytoskeleton …

During mitosis, spindle architecture alters as chromosomes segregate into daughter cells.
The microtubule crosslinker protein regulator of cytokinesis 1 (PRC1) is essential for spindle …

Mitotic kinesin-like protein 2 (MKLP2; also known as KIF20A) is a motor protein with a well-
established function in promoting cytokinesis. However, our results with siRNAs targeting …