Post-translational acetylation of lysine residues has emerged as a key regulatory
mechanism in all eukaryotic organisms. Originally discovered in 1963 as a unique …

Since their discovery in the 1980s and 1990s, the human protein lysine acetyltransferase
encoded by the paralogous p300 and CBP genes has received much interest. p300/CBP …

Post-translational modifications (PTMs) of histones provide a fine-tuned mechanism for
regulating chromatin structure and dynamics. PTMs can alter direct interactions between …

Protein lysine methylation is a distinct posttranslational modification that causes minimal
changes in the size and electrostatic status of lysine residues. Lysine methylation plays …

Abstract N 6-methyladenosine (m6A) is a modified base that has long been known to be
present in non-coding RNAs, ribosomal RNA, polyadenylated RNA and at least one …

PHD (plant homeodomain) zinc fingers are structurally conserved modules found in proteins
that modify chromatin as well as mediate molecular interactions in gene transcription. The …

Chromatin is a highly regulated nucleoprotein complex through which genetic material is
structured and maneuvered to elicit cellular processes, including transcription, cell division …

Plants have evolved many systems to sense their environment and to modify their growth
and development accordingly. One example is vernalization, the process by which flowering …

The recognition of distinctly modified histones by specialized 'effector'proteins constitutes a
key mechanism for transducing molecular events at chromatin to biological outcomes …

Large‐scale characterization of post‐translational modifications (PTM s), such as
phosphorylation, acetylation and ubiquitination, has highlighted their importance in the …