Wilms tumor (WT) is the most common renal malignancy of childhood. Global disparities in
WT have been reported with the highest incidence and lowest overall survival occurring in …

The category of globally accepted neoplasms of the kidney continues to expand.
Recognition of new entities is very important for care of patients and their families. For …

Mutations in the p53 gene, one of the most common genetic alterations in human cancer,
are implicated in tumorigenesis and tumour progression. Although p53 protein expression …

PURPOSE: A minority of children with Wilms tumor will experience tumor recurrence. In a
previous pilot study we found an association between expression of an immune …

Background: The few studies available in the literature on Wilms' tumour (WT) from sub-
Saharan Africa have reported a dismal outcome for children with the tumour. This study …

Background Mutations of the tumor suppressor gene p53 are commonly found in several
kinds of human cancer. In some types of neoplasms, accumulation of p53 protein has been …

BACKGROUND Nuclear unrest is a term applied to Wilms tumors (WT) with favorable
histology that show nuclear enlargement similar to that seen in anaplasia but with no …

Abstract Sub‐Saharan African children have an increased incidence of Wilms' tumor (WT)
and experience alarmingly poor outcomes. Although these outcomes are largely due to …

PURPOSE: We studied whether immunohistochemical expression of p53 in Wilms tumors
correlates with tumor aggressiveness. We also examined whether preoperative …

Although a correlation between anaplasia and mutations of the p53 tumor suppressor gene
has been found in Wilms' tumor (WT) a prognostic significance of p53 in WT remains largely …