The inflammatory microenvironment in hepatocellular carcinoma: a pivotal role for tumor‐associated macrophages

D Capece, M Fischietti, D Verzella… - BioMed research …, 2013 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the most common and aggressive human cancers
worldwide. HCC is an example of inflammation‐related cancer and represents a paradigm …

[HTML][HTML] Key players in pancreatic cancer-stroma interaction: Cancer-associated fibroblasts, endothelial and inflammatory cells

MFB Nielsen, MB Mortensen… - World journal of …, 2016 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is the most aggressive type of common cancers, and in 2014, nearly
40000 patients died from the disease in the United States. Pancreatic ductal …

NACSELD acute‐on‐chronic liver failure (NACSELD‐ACLF) score predicts 30‐day survival in hospitalized patients with cirrhosis

JG O'leary, KR Reddy, G Garcia‐Tsao, SW Biggins… - Hepatology, 2018 - journals.lww.com
Several highly effective, interferon‐free, direct‐acting antiviral (DAA)‐based regimens are
available for the treatment of chronic hepatitis C virus (HCV) infection. Despite impressive …

Matrix metalloproteinases in cancer: prognostic markers and therapeutic targets

P Vihinen, VM Kähäri - International journal of cancer, 2002 - Wiley Online Library
Degradation of extracellular matrix is crucial for malignant tumour growth, invasion,
metastasis and angiogenesis. Matrix metalloproteinases (MMPs) are a family of zinc …

Peptide-based biosensors

Q Liu, J Wang, BJ Boyd - Talanta, 2015 - Elsevier
Peptides have been used as components in biological analysis and fabrication of novel
biosensors for a number of reasons, including mature synthesis protocols, diverse structures …

Gemcitabine resistance in pancreatic ductal adenocarcinoma

Y Binenbaum, S Na'ara, Z Gil - Drug resistance updates, 2015 - Elsevier
Pancreatic ductal adenocarcinoma (PDA) ranks fourth among cancer related deaths. The
disappointing 5-year survival rate of below 5% stems from drug resistance to all known …

Chronic stress accelerates pancreatic cancer growth and invasion: a critical role for beta-adrenergic signaling in the pancreatic microenvironment

C Kim-Fuchs, CP Le, MA Pimentel… - Brain, behavior, and …, 2014 - Elsevier
Pancreatic cancer cells intimately interact with a complex microenvironment that influences
pancreatic cancer progression. The pancreas is innervated by fibers of the sympathetic …

Metastasis review: from bench to bedside

AM Alizadeh, S Shiri, S Farsinejad - Tumor biology, 2014 - Springer
Cancer is the final result of uninhibited cell growth that involves an enormous group of
associated diseases. One major aspect of cancer is when cells attack adjacent components …

Nerve fibers in the tumor microenvironment in neurotropic cancer—pancreatic cancer and cholangiocarcinoma

X Tan, S Sivakumar, J Bednarsch, G Wiltberger… - Oncogene, 2021 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) and cholangiocarcinoma (CCA) are both deadly
cancers and they share many biological features besides their close anatomical location …

[HTML][HTML] Iron and liver fibrosis: Mechanistic and clinical aspects

KJ Mehta, SJ Farnaud, PA Sharp - World journal of …, 2019 - ncbi.nlm.nih.gov
Liver fibrosis is characterised by excessive deposition of extracellular matrix that interrupts
normal liver functionality. It is a pathological stage in several untreated chronic liver …