MicroRNAs sculpt neuronal communication in a tight balance that is lost in neurological disease

KT Thomas, C Gross, GJ Bassell - Frontiers in Molecular …, 2018 - frontiersin.org
Since the discovery of the first microRNA 25 years ago, microRNAs (miRNAs) have emerged
as critical regulators of gene expression within the mammalian brain. miRNAs are small non …

Revisiting tandem repeats in psychiatric disorders from perspectives of genetics, physiology, and brain evolution

X Xiao, CY Zhang, Z Zhang, Z Hu, M Li, T Li - Molecular Psychiatry, 2022 - nature.com
Genome-wide association studies (GWASs) have revealed substantial genetic components
comprised of single nucleotide polymorphisms (SNPs) in the heritable risk of psychiatric …

A VNTR regulates miR-137 expression through novel alternative splicing and contributes to risk for schizophrenia

A Pacheco, R Berger, R Freedman, AJ Law - Scientific reports, 2019 - nature.com
The MIR137HG gene encoding microRNA-137 (miR-137) is genome-wide associated with
schizophrenia (SZ), however, the underlying molecular mechanisms remain unknown …

The MIR137 VNTR rs58335419 Is Associated With Cognitive Impairment in Schizophrenia and Altered Cortical Morphology

E Mahmoudi, JR Atkins, Y Quidé, WR Reay… - Schizophrenia …, 2021 - academic.oup.com
Genome-wide association studies (GWAS) of schizophrenia have strongly implicated a risk
locus in close proximity to the gene for miR-137. While there are candidate single-nucleotide …

Case report: Successful administration of cariprazine in a young, severely ill patient with recurrent relapses of schizophrenia and persistent negative symptoms

J Vrublevska - Frontiers in Psychiatry, 2023 - frontiersin.org
The present case report describes a young man diagnosed with schizophrenia and presents
a “revolving door”(RD) phenomenon. He was hospitalized in an acute psychiatric clinic three …

Two dopaminergic genes, DRD4 and SLC6A3, are associated with body mass index in a Colombian sample of young adults

Y González-Giraldo, ML Trujillo… - Archives of Physiology …, 2018 - Taylor & Francis
Obesity is becoming an epidemic in Latin American countries. Genetic analyses of
endophenotypes for obesity, such as body mass index (BMI), are quite useful for research. In …

A Study of Association of the MIR137 VNTR rs58335419 with Schizophrenia

GI Korovaitseva, IV Oleichik, TV Lezheiko… - Russian Journal of …, 2024 - Springer
The MIR137 gene encodes microRNA-137 (miR-137), which is a brain-enriched miR that is
highly expressed in various brain regions. miR-137 has been identified as a modulator of …

Situation awareness performance in healthy young adults is associated with a serotonin transporter gene polymorphism

Y González-Giraldo, RE González-Reyes… - Psychological …, 2018 - journals.sagepub.com
Background Situation awareness (SA) is defined in three levels: SA1 is the perception of the
elements in a specific context, SA2 is the comprehension of their meaning, and SA3 is the …

A functional SNP in the synaptic SNAP25 gene is associated with impulsivity in a Colombian sample

Y González-Giraldo, DA Forero - 3 Biotech, 2020 - Springer
The aim of the current study was to test the hypothesis that a functional polymorphism in the
synaptosome associated protein 25 (SNAP25) gene could be associated with impulsivity …

[PDF][PDF] Jelena Vrublevska

P Falkai, J Samochowiec, O Vasiliu - 2023 - science.rsu.lv
Schizophrenia is a complex, chronic, and debilitating disease with a worldwide lifetime
prevalence of around 5 per 1,000 persons and an estimated heritability of around 0.64 (1, 2) …