Glial fibrillary acidic protein: from intermediate filament assembly and gliosis to neurobiomarker

Z Yang, KKW Wang - Trends in neurosciences, 2015 - cell.com
Glial fibrillary acidic protein (GFAP) is an intermediate filament (IF) III protein uniquely found
in astrocytes in the central nervous system (CNS), non-myelinating Schwann cells in the …

GFAP in health and disease

J Middeldorp, EM Hol - Progress in neurobiology, 2011 - Elsevier
Glial fibrillary acidic protein (GFAP) is the main intermediate filament protein in mature
astrocytes, but also an important component of the cytoskeleton in astrocytes during …

Nestin is required for the proper self-renewal of neural stem cells

D Park, AP Xiang, FF Mao, L Zhang, CG Di, XM Liu… - Stem …, 2010 - academic.oup.com
The intermediate filament protein, nestin, is a widely employed marker of multipotent neural
stem cells (NSCs). Recent in vitro studies have implicated nestin in a number of cellular …

Schwann cells induce cancer cell dispersion and invasion

S Deborde, T Omelchenko, A Lyubchik… - The Journal of …, 2016 - Am Soc Clin Investig
Nerves enable cancer progression, as cancers have been shown to extend along nerves
through the process of perineural invasion, which carries a poor prognosis. Furthermore, the …

Development of myelinating glia: an overview

CD Cristobal, HK Lee - Glia, 2022 - Wiley Online Library
Myelin is essential to nervous system function, playing roles in saltatory conduction and
trophic support. Oligodendrocytes (OLs) and Schwann cells (SCs) form myelin in the central …

The use of keratin biomaterials derived from human hair for the promotion of rapid regeneration of peripheral nerves

P Sierpinski, J Garrett, J Ma, P Apel, D Klorig, T Smith… - Biomaterials, 2008 - Elsevier
The management of trauma-associated nerve defects is difficult because of the absence of
autologous donor motor or sensory nerves. Pre-clinical development and clinical experience …

GFAP at 50

A Messing, M Brenner - ASN neuro, 2020 - journals.sagepub.com
Fifty years have passed since the discovery of glial fibrillary acidic protein (GFAP) by
Lawrence Eng and colleagues. Now recognized as a member of the intermediate filament …

Much more than a scaffold: cytoskeletal proteins in neurological disorders

DC Muñoz-Lasso, C Romá-Mateo, FV Pallardó… - Cells, 2020 - mdpi.com
Recent observations related to the structure of the cytoskeleton in neurons and novel
cytoskeletal abnormalities involved in the pathophysiology of some neurological diseases …

Biology of Schwann cells

GJ Kidd, N Ohno, BD Trapp - Handbook of clinical neurology, 2013 - Elsevier
The fundamental roles of Schwann cells during peripheral nerve formation and regeneration
have been recognized for more than 100 years, but the cellular and molecular mechanisms …

Matrix metalloproteinase-2 and-9 as promising benefactors in development, plasticity and repair of the nervous system

M Verslegers, K Lemmens, I Van Hove… - Progress in neurobiology, 2013 - Elsevier
It has been 50years since Gross and Lapiere discovered collagenolytic activity during
tadpole tail metamorphosis, which was later on revealed as MMP-1, the founding member of …