The prevalence of metabolic diseases, including obesity, dyslipidemia, type 2 diabetes
mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD), is a severe burden in human …

Neurodevelopmental programming—the implementation of the genetic and epigenetic
blueprints that guide and coordinate normal brain development—requires tight regulation of …

Efforts to manipulate locus-specific histone acetylation to assess their causal role in gene
expression and cellular and behavioural phenotypes have been impeded by a lack of …

Background: Bisphenol A (BPA) is an endocrine disrupting chemical widely used in the
manufacture of polycarbonate plastic and epoxy resin to produce a multitude of consumer …

Alzheimer's disease (AD) is one of the most common neurodegenerative disorders, which is
characterized by the primary risk factor, age. Several attempts have been made to treat AD …

The etiology of autism spectrum disorder (ASD) remains unknown, but gene-environment
interactions, mediated through epigenetic mechanisms, are thought to be a key contributing …

Chromatin remodeling through histone acetyltransferase (HAT) and histone deactylase
(HDAC) enzymes affects fundamental cellular processes including the cell-cycle, cell …

Emerging evidence have shown the importance of gut microbiota in regulating brain
functions. The diverse molecular mechanisms involved in cross-talk between gut and brain …

Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with deficits
in social communication ability and repetitive behavior. The pathophysiological events …

At the end of the 20th century, analog systems in computer science have been widely
replaced by digital systems due to their higher computing power. Nevertheless, the question …