Individuals suffering from severe viral respiratory tract infections have recently emerged as
“at risk” groups for developing invasive fungal infections. Influenza virus is one of the most …

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Humans are highly susceptible to infection with respiratory viruses including respiratory
syncytial virus (RSV), influenza virus, human metapneumovirus, rhinovirus, coronavirus, and …

SARS-CoV-2 has caused morbidity and mortality across the globe. As the virus spreads,
new variants are arising that show enhanced capacity to bypass preexisting immunity. To …

Evidence has increasingly shown that the lungs are a major site of immune regulation. A
robust and highly regulated immune response in the lung protects the host from pathogen …

Regulatory T (Treg) cell modulation of adaptive immunity and tissue homeostasis is well
described; however, less is known about Treg cell-mediated regulation of the innate immune …

Influenza viruses have perplexed scientists for over a hundred years. Yearly vaccines limit
their spread, but they do not prevent all infections. Therapeutic treatments for those …

Foxp3+ regulatory T cells (Tregs) are a subset of CD4+ T cells that exert suppressive control
over other immune cells. Tregs are critical for preventing systemic autoimmunity and …

Obese individuals are at greater risk for hospitalization and death from infection with the
2009 pandemic H1N1 influenza virus (pH1N1). In this study, diet-induced and genetic …

Influenza A virus (IAV) is a relevant respiratory tract pathogen leading to a great number of
deaths and hospitalizations worldwide. Secondary bacterial infections are a very common …