Towards better understanding of KSHV life cycle: from transcription and posttranscriptional regulations to pathogenesis

L Yan, V Majerciak, ZM Zheng, K Lan - Virologica Sinica, 2019 - Springer
Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus-8
(HHV-8), is etiologically linked to the development of Kaposi's sarcoma, primary effusion …

KSHV microRNAs: tricks of the devil

J Qin, W Li, SJ Gao, C Lu - Trends in microbiology, 2017 - cell.com
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma
(KS), a vascular tumor frequently found in immunodeficient individuals. KSHV encodes 12 …

A DHX9-lncRNA-MDM2 interaction regulates cell invasion and angiogenesis of cervical cancer

X Ding, X Jia, C Wang, J Xu, SJ Gao, C Lu - Cell Death & Differentiation, 2019 - nature.com
Cervical cancer (CC) is the third most common carcinoma and the fourth leading cause of
cancer-associated mortality in women. Here, we report that MDM2-DHX9 interaction …

EBV-miR-BART1-5P activates AMPK/mTOR/HIF1 pathway via a PTEN independent manner to promote glycolysis and angiogenesis in nasopharyngeal carcinoma

X Lyu, J Wang, X Guo, G Wu, Y Jiao, OD Faleti… - PLoS …, 2018 - journals.plos.org
Abnormal metabolism and uncontrolled angiogenesis are two important characteristics of
malignant tumors. The occurrence of both events involves many key molecular changes …

SH3BGRL2 inhibits growth and metastasis in clear cell renal cell carcinoma via activating hippo/TEAD1-Twist1 pathway

L Yin, W Li, A Xu, H Shi, K Wang, H Yang, R Wang… - …, 2020 - thelancet.com
Background Clear cell renal cell carcinoma (ccRCC) is one of the most prevalent
malignancies in the world, and tumor metastasis is still the main reason for disease …

Down-regulation of HPGD by miR-146b-3p promotes cervical cancer cell proliferation, migration and anchorage-independent growth through activation of STAT3 and …

S Yao, J Xu, K Zhao, P Song, Q Yan, W Fan, W Li… - Cell death & …, 2018 - nature.com
While the application of early screening and HPV vaccines has reduced the incidence and
mortality rates of cervical cancer, it remains the third most common carcinoma and fourth …

The role of miRNAs in virus-mediated oncogenesis

Z Vojtechova, R Tachezy - International journal of molecular sciences, 2018 - mdpi.com
To date, viruses are reported to be responsible for more than 15% of all tumors worldwide.
The oncogenesis could be influenced directly by the activity of viral oncoproteins or by the …

[HTML][HTML] Therapeutic inhibition of miR-802 protects against obesity through AMPK-mediated regulation of hepatic lipid metabolism

Y Ni, Z Xu, C Li, Y Zhu, R Liu, F Zhang, H Chang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: The host-parasite relationship is based on subtle interplay between parasite
survival strategies and host defense mechanisms. It is well known that helminth infection …

Oncogenic KSHV-encoded interferon regulatory factor upregulates HMGB2 and CMPK1 expression to promote cell invasion by disrupting a complex lncRNA-OIP5 …

W Li, Q Wang, Q Feng, F Wang, Q Yan, SJ Gao… - PLoS …, 2019 - journals.plos.org
Kaposi's sarcoma (KS), a highly disseminated tumor of hyperproliferative spindle endothelial
cells, is the most common AIDS-associated malignancy caused by infection of Kaposi's …

CircRNA ARFGEF1 functions as a ceRNA to promote oncogenic KSHV-encoded viral interferon regulatory factor induction of cell invasion and angiogenesis by …

S Yao, X Jia, F Wang, L Sheng, P Song, Y Cao… - PLoS …, 2021 - journals.plos.org
Circular RNAs (circRNAs) are novel single-stranded noncoding RNAs that can decoy other
RNAs to inhibit their functions. Kaposi's sarcoma (KS), caused by oncogenic Kaposi's …