Effect of local zoledronate delivery on osseointegration: a systematic review of preclinical studies

SV Kellesarian, S Subhi ALHarthi… - Acta Odontologica …, 2017 - Taylor & Francis
Purpose: The aim of the present systematic review was to assess the effect of local
zoledronate (ZOL) delivery (topical or as implant surface coatings) on osseointegration …

Local delivery and controlled release of miR-34a loaded in hydroxyapatite/mesoporous organosilica nanoparticles composite-coated implant wire to accelerate bone …

X Guo, M Xue, F Chen, Q Guo, X Zhou, H Lin, Y Chen - Biomaterials, 2022 - Elsevier
Immediate mechanical stability is a prerequisite for fracture healing. In addition to bringing
immediate mechanical stability in fracture site, implants with bioactive coating can release …

[HTML][HTML] Zoledronic acid inhibits osteoclastogenesis and bone resorptive function by suppressing RANKL‑mediated NF‑κB and JNK and their downstream signalling …

XL Huang, C Liu, XM Shi… - Molecular …, 2022 - spandidos-publications.com
Targeting excessive osteoclast differentiation and activity is considered a valid therapeutic
approach for osteoporosis. Zoledronic acid (ZOL) plays a pivotal role in regulating bone …

Osseointegration pharmacology: a systematic mapping using artificial intelligence

M Mahri, N Shen, F Berrizbeitia, R Rodan, A Daer… - Acta Biomaterialia, 2021 - Elsevier
Clinical performance of osseointegrated implants could be compromised by the medications
taken by patients. The effect of a specific medication on osseointegration can be easily …

Comparison of osseointegration of five different surfaced titanium implants

S Dundar, F Yaman, A Bozoglan… - Journal of …, 2018 - journals.lww.com
The topography, chemical features, surface charge, and hydrophilic nature of titanium
implant surfaces are crucial factors for successful osseointegration. This study aimed to …

[HTML][HTML] Effects of restraint stress and high-fat diet on osseointegration of titanium implants: an experimental study

S Dundar, A Bozoglan, O Bulmus, S Tekin… - Brazilian Oral …, 2020 - SciELO Brasil
This study aimed to investigate the effects of chronic restraint stress (RS) and a high-fat diet
(HFD) on the osseointegration of titanium implants in a rat model. After the surgical insertion …

The effects of metformin on the bone filling ration around of TiAl6Va4 implants in non diabetic rats

TT Yıldırım, S Dündar, A Bozoğlan, T Karaman… - Journal of Oral Biology …, 2020 - Elsevier
Objectives In this research it was aimed to that evaluation of the effects of systemic
metformin administration on the periimplant bone tissue response of TiAl 6 Va 4 implants in …

Effect of primary stabilisation on osseointegration of implants with local and systemic zoledronic acid application

N Sokmen, S Dundar, A Bozoglan… - Journal of …, 2022 - journals.lww.com
Primary stabilization (PS) is defined as initial tight fit during the surgical placement of an
implant. Tight implant placement is quite difficult in cases where bone quality and quantity …

Effects of Different Levels of Restraint Stress on Bone–Implant Contact

A Bozoglan, S Dundar, TT Yildirim… - Journal of …, 2019 - journals.lww.com
This study examined the effects of different levels of chronic restraint stress on bone–
titanium implant contact in rats. This study included 32 adult female Sprague–Dawley rats …

The influence of high‐dose systemic zoledronate administration on osseointegration of implants with different surface topography

M Hou, RSB Lee, Z Du, SM Hamlet… - Journal of …, 2019 - Wiley Online Library
Aim To evaluate the influence of systemic zoledronate administration on the
osseointegration of titanium implants with different surface topography in rat maxillae …