Nanocarriers: A novel strategy for the delivery of CRISPR/Cas systems

F Hejabi, MS Abbaszadeh, S Taji, A O'Neill… - Frontiers in …, 2022 - frontiersin.org
In recent decades, clustered regularly interspaced short palindromic repeat/CRISPR-
associated protein (CRISPR/Cas) has become one of the most promising genome-editing …

CRISPR-Cas systems target endogenous genes to impact bacterial physiology and alter mammalian immune responses

Q Wu, L Cui, Y Liu, R Li, M Dai, Z Xia, M Wu - Molecular Biomedicine, 2022 - Springer
CRISPR-Cas systems are an immune defense mechanism that is widespread in archaea
and bacteria against invasive phages or foreign genetic elements. In the last decade …

Evolution of CRISPR-associated endonucleases as inferred from resurrected proteins

B Alonso-Lerma, Y Jabalera, S Samperio, M Morin… - Nature …, 2023 - nature.com
Clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9 is an
effector protein that targets invading DNA and plays a major role in the prokaryotic adaptive …

Legionella pneumophila Cas2 promotes the expression of small heat shock protein C2 that is required for thermal tolerance and optimal intracellular infection

JA Campbell, NP Cianciotto - Infection and immunity, 2022 - Am Soc Microbiol
Previously, we demonstrated that Cas2 encoded within the CRISPR-Cas locus of Legionella
pneumophila strain 130b promotes the ability of the Legionella pathogen to infect amoebal …

CRISPR-Cas adaptation in Escherichia coli

D Mitić, EL Bolt, I Ivančić-Baće - Bioscience reports, 2023 - portlandpress.com
Prokaryotes use the adaptive immunity mediated via the Clustered Regularly Interspaced
Short Palindromic Repeats and CRISPR associated (CRISPR-Cas) system for protection …

Identification of the EH CRISPR‐Cas9 system on a metagenome and its application to genome engineering

B Esquerra‐Ruvira, I Baquedano, R Ruiz… - Microbial …, 2023 - Wiley Online Library
Non‐coding RNAs (crRNAs) produced from clustered regularly interspaced short
palindromic repeats (CRISPR) loci and CRISPR‐associated (Cas) proteins of the …

Improving stability and specificity of CRISPR/Cas9 system by selective modification of guide RNAs with 2′-fluoro and locked nucleic acid nucleotides

L Sakovina, I Vokhtantsev, M Vorobyeva… - International Journal of …, 2022 - mdpi.com
The genome editing approach using the components of the CRISPR/Cas system has found
wide application in molecular biology, fundamental medicine and genetic engineering. A …

Identification of the EH CRISPR-Cas9 system on a metagenome and its application to genome engineering

B Esquerra, I Baquedano, R Ruiz, A Fernandez… - 2023 - rua.ua.es
Non-coding RNAs (crRNAs) produced from clustered regularly interspaced short
palindromic repeats (CRISPR) loci and CRISPR-associated (Cas) proteins of the prokaryotic …

[PDF][PDF] Precision Genome Editing: The Synergy of CRISPR and Nanotechnology in Cancer Treatment

A Vikal, R Maurya, S Bhowmik, P Patel, R Singh… - researchgate.net
In recent years, the applications of Clustered Regularly Interspaced Short Palindromic
Repeats (CRISPR) technology have revolutionized genetics and molecular biology. It has …