Migraine is a severe neurovascular disorder of which the pathophysiology is not yet fully
understood. Besides the role of inflammatory mediators that interact with the …

A systematic literature search was performed to identify studies that reported risk factors for
persistent pain after childbirth. Many studies have sought to identify risk factors for post …

While pain after trauma generally resolves, some trauma patients experience pain for
months to years after injury. An example, relevant to both combat and civilian settings, is …

Pain, particularly chronic pain, remains one of the most debilitating and difficult-to-treat
conditions in medicine. Chronic pain is difficult to treat, in part because it is associated with …

Posttraumatic headache (PTH) attributed to traumatic brain injury (TBI) is a secondary
headache developed within 7 days after head injury, and in a substantial number of patients …

Oxytocin and vasopressin are neurohypophyseal hormones with sequence similarity and
play a central role in bodily homeostatic regulation. Pain is currently understood to be an …

Simple Summary What is already known: Mg2+ levels modulate the affinity of oxytocin
receptors for oxytocin in vitro, low serum Mg2+ is correlated with migraine headache onset …

High rates of acute and chronic pain are associated with traumatic brain injury (TBI), but
mechanisms responsible for the association remain elusive. Recent data suggest …

Background Central sensitization is one of the characters of chronic migraine (CM). Aberrant
synaptic plasticity can induce central sensitization. Oxytocin (OT), which is a hypothalamic …

Pediatric traumatic brain injury (TBI) results in heightened risk for social deficits that can
emerge during adolescence and adulthood. A moderate TBI in male and female rats on …