Mechanisms involved in the neurotoxic effects of environmental toxicants such as polychlorinated biphenyls and brominated flame retardants

F Fonnum, E Mariussen - Journal of neurochemistry, 2009 - Wiley Online Library
Many toxic substances have been distributed to the environment, some of which have
properties that promote accumulation and biomagnification in living organisms …

Neurotoxicity of persistent organic pollutants: possible mode (s) of action and further considerations

PRS Kodavanti - Dose-response, 2005 - journals.sagepub.com
Persistent organic pollutants (POPs) are long-lived toxic organic compounds and are of
major concern for human and ecosystem health. Although the use of most POPs is banned …

Cognitive development in preschool children prenatally exposed to PCBs and MeHg

PW Stewart, J Reihman, EI Lonky, TJ Darvill… - Neurotoxicology and …, 2003 - Elsevier
A number of epidemiological studies have shown predictive relationships between prenatal
exposure to polychlorinated biphenyls (PCBs) and subtle deficits in cognitive development …

Neurochemical targets and behavioral effects of organohalogen compounds: an update

E Mariussen, F Fonnum - Critical reviews in toxicology, 2006 - Taylor & Francis
Organohalogen compounds (OHCs) have been used and still are used extensively as
pesticides, flame retardants, hydraulic fluids, and in other industrial applications. These …

Human developmental neurotoxicity of methylmercury: impact of variables and risk modifiers

AF Castoldi, C Johansson, N Onishchenko… - Regulatory Toxicology …, 2008 - Elsevier
Methylmercury (MeHg) is a widespread environmental and food toxicant which has long
been known to affect neurodevelopment in both humans and experimental animals. Risk …

The polychlorinated biphenyl mixture aroclor 1254 induces death of rat cerebellar granule cells: the involvement of the N-methyl-D-aspartate receptor and reactive …

E Mariussen, O Myhre, T Reistad, F Fonnum - Toxicology and applied …, 2002 - Elsevier
Polychlorinated biphenyls (PCBs) are widespread persistent environmental contaminants
that display a complex spectrum of toxicological properties, including neurotoxicity. The …

Mercury in fishes of Alaska, with emphasis on subsistence species

SC Jewett, LK Duffy - Science of the Total Environment, 2007 - Elsevier
In the north, the presence of mercury (Hg) in food leading to chronic exposure is a scientific,
economic and political issue. Guidelines have been established for the safe consumption of …

Response inhibition during differential reinforcement of low rates (DRL) schedules may be sensitive to low-level polychlorinated biphenyl, methylmercury, and lead …

PW Stewart, DM Sargent, J Reihman… - Environmental …, 2006 - ehp.niehs.nih.gov
Background Animal studies have shown that exposure to common, low-level environmental
contaminants [eg, polychlorinated biphenyls (PCBs), lead] causes excessive and …

Motor function following developmental exposure to PCBS and/or MEHG

CS Roegge, SL Schantz - Neurotoxicology and teratology, 2006 - Elsevier
Recent studies raise concern for combined exposure to polychlorinated biphenyls (PCBs)
and methylmercury (MeHg), two environmental contaminants that are found in fish and …

Motor impairment in rats exposed to PCBs and methylmercury during early development

CS Roegge, VC Wang, BE Powers… - Toxicological …, 2004 - academic.oup.com
Epidemiological and laboratory studies indicate that polychlorinated biphenyls (PCBs) and
methyl mercury (MeHg) may have additive or interactive adverse effects on nervous system …