Imidazole ring is an important five‐membered aromatic heterocycle widely present in natural
products and synthetic molecules. The unique structural feature of imidazole ring with …

Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole
ring are readily able to bind with a variety of enzymes and receptors in biological system via …

Cancer is known as one of the main causes of death in the world; and many compounds
have been synthesized to date with potential use in cancer therapy. Thiazole is a versatile …

This review provides an overview of the discovery, structures, and biological activities of
anticancer natural products that act by inhibiting or promoting the assembly of tubulin to …

Cancer is a leading cause of death worldwide. Even after the availability of numerous drugs
and treatments in the market, scientists and researchers are focusing on new therapies …

The tetrazole ring is an important pharmacophore. It is a structural component in many
drugs, drug candidates (or lead compounds) and various biochemical reagents. This review …

Stilbene is an abundant structural scaffold in nature, and stilbene‐based compounds have
been widely reported for their biological activity. Notably,(E)‐resveratrol and its natural …

The antitumor efficacy of Chinese herbal medicines has been widely recognized. Leading
compounds such as sterols, glycosides, flavonoids, alkaloids, terpenoids …

Tetrazole cycle is a promising pharmacophore fragment frequently used in the development
of novel drugs. This moiety is a stable, practically non-metabolized bioisosteric analog of …

Tubulin, the major structural component of microtubules, is a target for the development of
anticancer agents. Two series of 1, 5-diaryl substituted 1, 2, 3, 4-tetrazoles were concisely …