Epigenetic, along with genetic mechanisms, is essential for natural evolution and
maintenance of specific patterns of gene expression in mammalians. Global epigenetic …

Myelodysplastic syndromes (MDS) are malignant clonal disorders of haematopoietic stem
cells and their microenvironment, affecting older individuals (median age∼ 70 years) …

In this review, we focus on bioinformatic oncology as an integrative discipline that
incorporates knowledge from the mathematical, physical, and computational fields to further …

We report an ultra-low fouling surface plasmon resonance imaging (SPRi) biosensor for the
rapid simultaneous detection of multiple miRNAs in erythrocyte lysate (EL) at subpicomolar …

INTRODUCTION: Emerging evidence suggest that microRNAs could serve as non-invasive
biomarker for cancer patients. Our study was designed to analyze circulating serum …

DNA methylation and histone modification are epigenetic mechanisms that result in altered
gene expression and cellular phenotype. The exact role of methylation in myelodysplastic …

The Werner syndrome (WS) is a prototypic adult Mendelian progeroid syndrome in which
signs of premature aging are associated with genomic instability and an elevated risk of …

MicroRNAs (miRNAs) have become one of the hottest topics in biology over recent years,
but remarkably have only been formally recognized for just over 10years. These …

Myelodysplastic syndromes (MDSs) consist of a family of hematopoietic stem cell (HSC)
disorders characterized by ineffective differentiation of hematopoietic progenitors, bone …

Myelodysplastic syndromes (MDS) are characterized by impaired proliferation and
differentiation of hematopoietic stem cells. The participation of toll-like receptor (TLR) …