The cycling and aging mouse female reproductive tract at single-cell resolution

I Winkler, A Tolkachov, F Lammers, P Lacour… - Cell, 2024 - cell.com
The female reproductive tract (FRT) undergoes extensive remodeling during reproductive
cycling. This recurrent remodeling and how it shapes organ-specific aging remains poorly …

Multi-omics analyses and machine learning prediction of oviductal responses in the presence of gametes and embryos

RM Finnerty, DJ Carulli, A Hegde, Y Wang, F Baodu… - …, 2024 - pmc.ncbi.nlm.nih.gov
The oviduct is the site of fertilization and preimplantation embryo development in mammals.
Evidence suggests that gametes alter oviductal gene expression. To delineate the adaptive …

Hedgehog signaling is required for endometrial remodeling and myometrial homeostasis in the cycling mouse uterus

EC Roberson, NK Tran, AN Godambe, H Mark… - Iscience, 2023 - cell.com
Decades of work demonstrate that the mammalian estrous cycle is controlled by cycling
steroid hormones. However, the signaling mechanisms that act downstream, linking …

[HTML][HTML] Molecular Evolution of the Ovgp1 Gene in the Subfamily Murinae

M Balastegui-Alarcón, C Moros-Nicolás, J Ballesta… - Animals, 2024 - mdpi.com
OGP, encoded by the Ovgp1 gene, is the major non-serum oviductal protein in most
mammals. In the genome of Rattus norvegicus, Ovgp1 has been identified as a …

Region-specific roles of oviductal motile cilia in oocyte/embryo transport and fertility

DM Scully, T Xia, GR Musina, MA McCown… - Biology of …, 2025 - academic.oup.com
The physiological and clinical importance of motile cilia in reproduction is well recognized,
however, the specific role they play in transport through the oviduct and how ciliopathies …

The function and decline of the female reproductive tract at single-cell resolution

I Winkler, A Tolkachov, F Lammers, P Lacour… - bioRxiv, 2022 - biorxiv.org
The female reproductive tract (FRT) undergoes extensive remodeling during each
reproductive cycle, regulated by systemic changes in sex hormones. Whether this recurrent …

[HTML][HTML] Multiple cell types in the oviduct express the prolactin receptor

KC Radecki, MJ Ford, HR Phillipps… - FASEB …, 2022 - ncbi.nlm.nih.gov
Little is known about the physiological role of prolactin in the oviduct. Examining mRNA for
all four isoforms of the prolactin receptor (PRLR) in mice by functional oviduct segment and …

Iterative remodeling of the mouse uterus requires Hedgehog signaling

EC Roberson, NK Tran, AN Godambe, T Rust… - BioRxiv, 2022 - biorxiv.org
The adult uterus regenerates in the human during the menstrual cycle, and remodels in the
mouse during the estrous cycle. Decades of work has demonstrated that this process is …

Gene expression profile analysis of subregions of the adult female reproductive tract in the brown anole, Anolis sagrei

BK Kircher, B Liu, MD Bramble, MM Moses… - …, 2024 - rep.bioscientifica.com
In brief Modes of reproduction across limbed vertebrates are diverse, but the molecular
mechanisms required for the development and maintenance of reproductive tract tissue …

The Oviduct, Sperm, and Eggs: A Multiomics AI Integrated In Vivo Characterization During Pregnancy

R Finnerty - 2024 - search.proquest.com
The oviduct comprises 4 main regions: infundibulum (oocyte pick-up), ampulla (fertilization),
isthmus (sperm capacitation and reservoir, preimplantation embryonic development), and …