Harmonizing the neurobiology and treatment of obsessive-compulsive disorder

WK Goodman, EA Storch… - American Journal of …, 2021 - Am Psychiatric Assoc
Obsessive-compulsive disorder (OCD) is a common, chronic, and oftentimes disabling
disorder. The only established first-line treatments for OCD are exposure and response …

Obsessive–compulsive disorder: an integrative genetic and neurobiological perspective

DL Pauls, A Abramovitch, SL Rauch… - Nature Reviews …, 2014 - nature.com
Obsessive–compulsive disorder (OCD) is characterized by repetitive thoughts and
behaviours that are experienced as unwanted. Family and twin studies have demonstrated …

Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways

MR Milad, SL Rauch - Trends in cognitive sciences, 2012 - cell.com
Obsessive-compulsive disorder (OCD) affects approximately 2–3% of the population and is
characterized by recurrent intrusive thoughts (obsessions) and repetitive behaviors or …

The neurocircuitry of fear, stress, and anxiety disorders

LM Shin, I Liberzon - Neuropsychopharmacology, 2010 - nature.com
Anxiety disorders are a significant problem in the community, and recent neuroimaging
research has focused on determining the brain circuits that underlie them. Research on the …

Brain circuitry of compulsivity

OA Van den Heuvel, G van Wingen… - European …, 2016 - Elsevier
Compulsivity is associated with alterations in the structure and the function of parallel and
interacting brain circuits involved in emotional processing (involving both the reward and the …

Voxel-wise meta-analysis of grey matter changes in obsessive–compulsive disorder

J Radua, D Mataix-Cols - The British Journal of Psychiatry, 2009 - cambridge.org
BackgroundSpecific cortico-striato-thalamic circuits are hypothesised to mediate the
symptoms of obsessive–compulsive disorder (OCD), but structural neuroimaging studies …

Functional imaging of brain responses to pain. A review and meta-analysis (2000)

R Peyron, B Laurent, L Garcia-Larrea - Neurophysiologie Clinique/Clinical …, 2000 - Elsevier
Brain responses to pain, assessed through positron emission tomography (PET) and
functional magnetic resonance imaging (fMRI) are reviewed. Functional activation of brain …

The functional neuroanatomy of emotion and affective style

RJ Davidson, W Irwin - Trends in cognitive sciences, 1999 - cell.com
Recently, there has been a convergence in lesion and neuroimaging data in the
identification of circuits underlying positive and negative emotion in the human brain …

The primate basal ganglia: parallel and integrative networks

SN Haber - Journal of chemical neuroanatomy, 2003 - Elsevier
The basal ganglia and frontal cortex operate together to execute goal directed behaviors.
This requires not only the execution of motor plans, but also the behaviors that lead to this …

Emotion, plasticity, context, and regulation: perspectives from affective neuroscience.

RJ Davidson, DC Jackson, NH Kalin - Psychological bulletin, 2000 - psycnet.apa.org
The authors present an overview of the neural bases of emotion. They underscore the role of
the prefrontal cortex (PFC) and amygdala in 2 broad approach-and withdrawal-related …