Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …

Cancer stem cells (CSCs) are a population of self-renewal cells with high tumorigenic
potency. CSCs can adopt easily with changes in the nearby milieu, and are more resistant to …

Cell death provides host defense and maintains homeostasis. Zα-containing molecules are
essential for these processes. Z-DNA binding protein 1 (ZBP1) activates inflammatory cell …

Background Copper ions are essential for cellular physiology. Cuproptosis is a novel
method of copper-dependent cell death, and the cuproptosis-based signature for glioma …

Abstract N 6-Methyladenosine (m6A) is the most abundant modification of mammalian
mRNAs. RNA methylation fine tunes RNA stability and translation, altering cell fate. The fat …

Ovarian cancer is the leading cause of gynecological malignancy–related deaths, due to its
widespread intraperitoneal metastases and acquired chemoresistance. Mesothelial cells are …

Resistance to cell death is a hallmark of cancer. Immunotherapy, particularly immune
checkpoint blockade therapy, drives immune-mediated cell death and has greatly improved …

Simple Summary Cancer is one of the hardest pathologies to fight, being one of the main
causes of death worldwide despite the constant development of novel therapeutic strategies …

One of the current stumbling blocks in our fight against cancer is the development of
acquired resistance to therapy, which is attributable to approximately 90% of cancer-related …

Programmed cell death (PCD) has been a major area of constantly growing interest over the
last three decades. Originally, apoptosis was considered the only mechanistic pathway for …