Cancer metastasis is the primary cause of morbidity and mortality in cancer as it remains the
most complicated, devastating, and enigmatic aspect of cancer. Several decades of …

Background. Serum alkaline phosphatase (SALP) is commonly elevated in osteosarcoma
patients. A number of studies have investigated the prognostic role of SALP level in patients …

Canine osteosarcoma (OS) is an aggressive tumour that accounts for approximately 90% of
primary bone tumours in the dog. Although the standard treatments (including limb …

Estrogen promotes breast cancer metastasis. However, the detailed mechanism remains
largely unknown. The actin binding protein ezrin is a key component in tumor metastasis …

More and more studies have investigated the effects of Ezrin expression level on the
prognostic role in various tumors. However, the results remain controversial rather than …

Due to a lack of novel therapies and biomarkers, the clinical outcomes of osteosarcoma
patients have not significantly improved for decades. The advancement of mass …

Background The polycomb transcription factor Yin Yang 1 (YY1) overexpression can be
causally implicated in experimental tumor growth and metastasization. To date, there is no …

Simple Summary The standard method for the diagnosis and monitoring of osteosarcoma is
biopsy and tumor imaging, which causes discomfort to patients and is difficult to repeat. A …

Background To evaluate the EZR (ezrin) gene expression in breast cancer and correlation
with the prognosis through bioinformatics analysis and immunohistochemistry assay …

WWOX gene is located in FRA16D, the highly affected chromosomal fragile site. Its tumor
suppressor activity has been proposed on a basis of numerous genomic alterations reported …